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1. WO2020006367 - METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING METABOLIC SYNDROME INDUCED BY ANTIPSYCHOTIC TREATMENT AND RELATED DISEASES AND CONDITIONS

Publication Number WO/2020/006367
Publication Date 02.01.2020
International Application No. PCT/US2019/039747
International Filing Date 28.06.2019
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
217
Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
54
having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
56
with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
58
with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
233
Carboxylic acid amides
01
having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
34
having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
35
with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
36
having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
235
Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
70
having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
72
with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
76
of an unsaturated carbon skeleton
C07C 217/58 (2006.01)
C07C 233/36 (2006.01)
C07C 235/76 (2006.01)
CPC
A61K 31/381
C07C 217/58
C07C 233/36
C07C 235/76
Applicants
  • TUFTS MEDICAL CENTER, INC. [US/US]; 800 Washington Street Boston, MA 02111, US
Inventors
  • OXENKRUG, Gregory; US
  • SUMMERGRAD, Paul; US
Agents
  • MICHAUD, Susan, M.; US
Priority Data
62/692,08929.06.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING METABOLIC SYNDROME INDUCED BY ANTIPSYCHOTIC TREATMENT AND RELATED DISEASES AND CONDITIONS
(FR) PROCÉDÉS ET COMPOSITIONS POUR PRÉVENIR ET TRAITER UN SYNDROME MÉTABOLIQUE INDUIT PAR UN TRAITEMENT ANTIPSYCHOTIQUE ET DES MALADIES ET ÉTATS ASSOCIÉS
Abstract
(EN)
The invention provides methods and compositions for use in the prevention and treatment of antipsychotic medication-induced metabolic syndrome (MetS) and diseases and conditions related to MetS.
(FR)
L'invention concerne des procédés et des compositions destinés à être utilisés pour prévenir et traiter un syndrome métabolique (MetS) induit par un médicament antipsychotique et des maladies et des états associés à un MetS.
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