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1. (WO2020006197) METHODS FOR ANALYZING DNA IN URINE
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2020/006197 International Application No.: PCT/US2019/039449
Publication Date: 02.01.2020 International Filing Date: 27.06.2019
IPC:
C12N 15/11 (2006.01) ,C12Q 1/6806 (2018.01) ,C12Q 1/6827 (2018.01) ,C12Q 1/686 (2018.01) ,C12Q 1/6886 (2018.01) ,G01N 33/574 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
[IPC code unknown for C12Q 1/6806][IPC code unknown for C12Q 1/6827][IPC code unknown for C12Q 1/686][IPC code unknown for C12Q 1/6886]
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
Applicants:
THE TRUSTEES OF INDIANA UNIVERSITY [US/US]; 107 S. Indiana Avenue Bloomington, Indiana 47405, US
Inventors:
LAUTENSCHLAEGER, Tim; US
Agent:
ADDISON, Bradford G.; US
STETZER, Elizabeth L.; US
Priority Data:
62/690,49227.06.2018US
Title (EN) METHODS FOR ANALYZING DNA IN URINE
(FR) PROCÉDÉS D'ANALYSE DE L'ADN DANS L'URINE
Abstract:
(EN) The present disclosure relates to methods of extracting DNA from urine and methods of analyzing DNA in a urine sample. Methods are provided for extracting ctDNA from a urine sample and analyzing the extracted ctDNA for mutations indicative of a disease. The disclosure also relates to compositions for use in such methods.
(FR) La présente invention concerne des procédés d'extraction de l'ADN contenu dans l'urine et des procédés d'analyse de l'ADN dans un échantillon d'urine. L'invention concerne également des procédés d'extraction de l'ADNtc contenu dans un échantillon d'urine et d'analyse de l'ADNtc extrait à la recherche de mutations révélant une maladie. L'invention concerne également des compositions destinées à être utilisées dans de tels procédés.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)