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1. WO2020006092 - FILM FORMULATIONS CONTAINING DEXMEDETOMIDINE AND METHODS OF PRODUCING THEM

Publication Number WO/2020/006092
Publication Date 02.01.2020
International Application No. PCT/US2019/039268
International Filing Date 26.06.2019
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
70
Web, sheet or filament bases
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
4174
Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
38
Cellulose; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
A61K 9/70 (2006.01)
A61K 31/4174 (2006.01)
A61K 47/38 (2006.01)
A61P 25/00 (2006.01)
CPC
A61K 31/4174
A61K 47/34
A61K 47/38
A61K 9/0056
A61K 9/7007
A61P 25/22
Applicants
  • BIOXCEL THERAPEUTICS, INC. [US/US]; 555 Long Wharf Drive New Haven, Connecticut 06511, US
  • ARX, LLC [US/US]; 400 Seaks Run Road Glen Rock, Pennsylvania 17327, US
Inventors
  • KAKUMANU, Vasukumar; IN
  • YOCCA, Frank; US
  • LATHIA, Chetan Dalpatbhai; US
  • HANLEY, David Christian; US
  • BARNHART, Scott David; US
Agents
  • BROWN, Fraser D.; US
  • CAFFIN, Lee; US
  • TUSCAN, Michael S.; US
Priority Data
62/690,40727.06.2018US
62/693,72603.07.2018US
62/767,42214.11.2018US
62/787,64902.01.2019US
62/798,84230.01.2019US
62/849,74717.05.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FILM FORMULATIONS CONTAINING DEXMEDETOMIDINE AND METHODS OF PRODUCING THEM
(FR) FORMULATIONS DE FILM CONTENANT DE LA DEXMÉDÉTOMIDINE ET LEURS PROCÉDÉS DE PRODUCTION
Abstract
(EN)
Disclosed herein is a self-supporting, dissolvable, film containing dexmedetomidine or a pharmaceutically acceptable salt thereof. The film is administered orally to treat various conditions, particularly agitation, by transmucosal delivery of the active agent.
(FR)
L'invention concerne un film, soluble, autoportant, contenant de la dexmédétomidine ou un sel pharmaceutiquement acceptable de celle-ci. Le film est administré par voie orale pour traiter diverses affections, en particulier une agitation, par administration transmucosale de l'agent actif.
Latest bibliographic data on file with the International Bureau