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1. WO2020006017 - TIOTROPIUM FORMULATION AND INHALER

Publication Number WO/2020/006017
Publication Date 02.01.2020
International Application No. PCT/US2019/039133
International Filing Date 26.06.2019
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
12
Aerosols; Foams
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
46
8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
535
having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
15
Inhalators
A61K 9/12 (2006.01)
A61K 31/46 (2006.01)
A61K 31/535 (2006.01)
A61M 15/00 (2006.01)
CPC
A61K 31/46
A61K 31/535
A61K 47/10
A61K 47/12
A61K 47/24
A61K 9/008
Applicants
  • 3M INNOVATIVE PROPERTIES COMPANY [US/US]; 3M Center Post Office Box 33427 Saint Paul, Minnesota 55133-3427, US
Inventors
  • SLOWEY, Alexander D.; GB
  • COCKS, Philip M.; GB
  • PATEL, Neha A.; GB
Agents
  • RINGSRED, Ted K.,; US
  • FLORCZAK, Yen Tong; US
  • BLANK, Colene H.,; US
  • HARTS, Dean M. ,; US
  • LEVINSON, Eric D.,; US
  • MAKI, Eloise J.,; US
  • NOWAK, Sandra K.,; US
Priority Data
62/690,67727.06.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TIOTROPIUM FORMULATION AND INHALER
(FR) FORMULATION DE TIOTROPIUM ET INHALATEUR
Abstract
(EN)
A metered dose inhaler equipped with a metering valve and having an aerosol canister containing a pharmaceutical composition comprising propellant, ethanol, citric acid, and tiotropium or a pharmaceutically acceptable salt or solvate thereof dissolved in the composition, wherein the aerosol canister has an internal surface that is a non-metal material that is in contact with the pharmaceutical composition.
(FR)
L'invention concerne un inhalateur-doseur équipé d'une valve doseuse et possédant une cartouche d'aérosol contenant une composition pharmaceutique comprenant un gaz propulseur, de l'éthanol, de l'acide citrique, et du tiotropium ou un sel ou un solvate pharmaceutiquement acceptable de celui-ci dissous dans la composition, la cartouche d'aérosol présentant une surface interne qui est un matériau non métallique qui est en contact avec la composition pharmaceutique.
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