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1. WO2020004980 - METHOD FOR PREPARING PNA OLIGOMER

Publication Number WO/2020/004980
Publication Date 02.01.2020
International Application No. PCT/KR2019/007823
International Filing Date 27.06.2019
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
06
using protecting groups or activating agents
C07K 14/00 (2006.01)
C07K 1/06 (2006.01)
CPC
C07K 1/06
C07K 14/00
Applicants
  • 주식회사 시선바이오머티리얼스 SEASUNBIO MATERIALS [KR/KR]; 대전시 유성구 테크노1로 11-3, N517호 #N517,11-3, Techno 1-ro Yuseong-Gu Daejeon 34015, KR
Inventors
  • 박희경 PARK, Heekyung; KR
  • 홍인석 HONG, In Seok; KR
  • 조군호 JOE, Goon Ho; KR
  • 김용태 KIM, Yongtae; KR
Agents
  • 특허법인 플러스 PLUS INTERNATIONAL IP LAW FIRM; 대전시 서구 한밭대로 809, 10층 10F, 809, Hanbat-daero Seo-Gu Daejeon 35209, KR
Priority Data
10-2018-007411127.06.2018KR
10-2019-007655526.06.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) METHOD FOR PREPARING PNA OLIGOMER
(FR) PROCÉDÉ DE PRÉPARATION D'UN OLIGOMÈRE D'UN ACIDE NUCLÉIQUE PEPTIDIQUE (PNA)
(KO) PNA 올리고머의 제조방법
Abstract
(EN)
The present invention provides a method for preparing a PNA oligomer. More specifically, the present invention can prepare a PNA oligomer which is easily separable from byproducts through a simple and short process by using PNA dimers, PNA trimers or PNA tetramers, and which has extremely high yields and purity.
(FR)
La présente invention concerne un procédé de préparation d'un oligomère d'un acide nucléique peptidique (PNA). Plus particulièrement, la présente invention permet de préparer un oligomère de PNA qui est facilement séparable des sous-produits par un procédé simple et court par l'utilisation de dimères de PNA, de trimères de PNA ou de tétramères de PNA, et qui présente des rendements extrêmement élevés et une pureté supérieure.
(KO)
본 발명은 PNA 올리고머의 제조방법을 제공하는 것으로, 보다 구체적으로, PNA 이량체, PNA 삼량체 또는 PNA 사량체를 이용함으로써 단순하고 짧은 공정으로 부산물과 분리가 용이하며, 수율 및 순도가 극히 높은 PNA 올리고머를 제조할 수 있다.
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