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1. WO2020004668 - SEPARATING AGENT

Publication Number WO/2020/004668
Publication Date 02.01.2020
International Application No. PCT/JP2019/026134
International Filing Date 01.07.2019
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
17
Carrier-bound or immobilised peptides; Preparation thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
42
against immunoglobulins (anti-idiotypic antibodies)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
12
Genes encoding animal proteins
13
Immunoglobulins
C07K 17/00 (2006.01)
C07K 16/42 (2006.01)
G01N 33/48 (2006.01)
C12N 15/13 (2006.01)
CPC
C07K 16/42
C07K 17/00
G01N 33/48
Applicants
  • 国立大学法人京都工芸繊維大学 NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY [JP/JP]; 京都府京都市左京区松ヶ崎橋上町1番地 1, Matsugasaki Hashikami-cho, Sakyo-ku, Kyoto-shi, Kyoto 6068585, JP
  • 株式会社ダイセル DAICEL CORPORATION [JP/JP]; 大阪府大阪市北区大深町3番1号 3-1, Ofuka-cho, Kita-ku, Osaka-shi, Osaka 5300011, JP
Inventors
  • 熊田 陽一 KUMADA, Yoichi; JP
  • 大倉 裕道 OKURA, Hiromichi; JP
  • 内村 誠一 UCHIMURA, Seiichi; JP
Agents
  • 丹羽 武司 NIWA, Takeshi; JP
  • 佐貫 伸一 SANUKI, Shinichi; JP
  • 菅家 博英 KANKE, Hirohide; JP
  • 今堀 克彦 IMABORI, Katsuhiko; JP
Priority Data
2018-12397829.06.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) SEPARATING AGENT
(FR) AGENT DE SÉPARATION
(JA) 分離剤
Abstract
(EN)
[Problem] To provide a separating agent with enhanced dynamic binding capacity (DBC) with respect to a target substance. [Solution] Said problem is solved by a separating agent comprising a carrier and a protein, wherein the protein is a predetermined protein, and the surface of the carrier and the added lysine residue in the protein are bonded via chemical bonding.
(FR)
Le problème décrit par la présente invention est de fournir un agent de séparation ayant une capacité de liaison dynamique améliorée (DBC) par rapport à une substance cible. La solution selon l'invention porte sur un agent de séparation comprenant un véhicule et une protéine, la protéine étant une protéine prédéterminée, et la surface du véhicule et le résidu de lysine ajouté dans la protéine étant liés par liaison chimique.
(JA)
本発明の課題は、目的物質に対する動的結合量(DBC)が向上した分離剤の提供であり、該課題を、担体とタンパク質とを含む分離剤であって、該タンパク質は、所定のタンパク質であり、該担体の表面と該タンパク質における該付加されたリジン残基とが化学結合によって結合している、分離剤で解決する。
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