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1. WO2020003196 - PHARMACEUTICAL COMPOSITION OF AXITINIB

Publication Number WO/2020/003196
Publication Date 02.01.2020
International Application No. PCT/IB2019/055454
International Filing Date 27.06.2019
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
4439
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
A61K 31/4439 (2006.01)
A61K 9/20 (2006.01)
A61K 9/00 (2006.01)
C07D 401/06 (2006.01)
CPC
A61K 31/4439
A61K 9/20
A61K 9/2009
A61K 9/2018
A61K 9/284
Applicants
  • ALEMBIC PHARMACEUTICALS LIMITED [IN/IN]; Alembic Research Center, Alembic Road, Vadodara, Gujarat 390003, IN
Inventors
  • KHAPRA, Dr. Pankaj Kumar; IN
  • DABRA, Dr. Rahul; IN
  • GHOSH, Soumik; IN
  • ALI, Sartaj; IN
Priority Data
20182102413428.06.2018IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION OF AXITINIB
(FR) COMPOSITION PHARMACEUTIQUE D'AXITINIB
Abstract
(EN)
The present subject matter is directed to a stable pharmaceutical composition comprising axitinib in crystalline polymorphic form IV and one or more pharmaceutically acceptable excipients. In particular, the composition is bioequivalent to the commercially available axitinib tablets (INLYTA®).
(FR)
La présente invention concerne une composition pharmaceutique stable comprenant de l'axitinib sous forme polymorphe cristalline IV et un ou plusieurs excipients pharmaceutiquement acceptables. En particulier, la composition est bioéquivalente aux comprimés d'axitinib disponibles dans le commerce (INLYTA®).
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