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1. WO2020003006 - COMPOSITIONS AND METHODS FOR GENOMIC EDITING BY INSERTION OF DONOR POLYNUCLEOTIDES

Publication Number WO/2020/003006
Publication Date 02.01.2020
International Application No. PCT/IB2019/000833
International Filing Date 28.06.2019
IPC
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
87
Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
90
Stable introduction of foreign DNA into chromosome
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C12N 15/11 (2006.01)
C12N 15/90 (2006.01)
A61K 31/7088 (2006.01)
A61K 48/00 (2006.01)
CPC
A61K 48/005
C12N 15/11
C12N 15/111
C12N 15/907
C12N 2310/18
C12N 2310/20
Applicants
  • CRISPR THERAPEUTICS AG [CH/CH]; Baarerstrasse 14 6300 Zug, CH
Inventors
  • CARLO, Troy, Dean; CH
  • BOGORAD, Roman, Lvovitch; CH
Agents
  • VOSSIUS & PARTNER; Patentanwälte Rechtsanwälte mbB Siebertstrasse 3 81675 München, DE
Priority Data
62/691,57328.06.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR GENOMIC EDITING BY INSERTION OF DONOR POLYNUCLEOTIDES
(FR) COMPOSITIONS ET PROCÉDÉS D'ÉDITION GÉNOMIQUE PAR INSERTION DE POLYNUCLÉOTIDES DONNEURS
Abstract
(EN)
The present disclosure provides donor polynucleotides, genome editing systems, methods, and kits which correct or induce a mutation in a gDNA.
(FR)
La présente invention concerne des polynucléotides donneurs, des systèmes d'édition génomique, des procédés et des kits permettant de corriger ou d'induire une mutation dans un ADNg.
Latest bibliographic data on file with the International Bureau