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1. (WO2020002905) CANCER THERAPY
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2020/002905 International Application No.: PCT/GB2019/051794
Publication Date: 02.01.2020 International Filing Date: 25.06.2019
IPC:
A61K 39/395 (2006.01) ,A61K 35/74 (2015.01) ,C07K 16/28 (2006.01) ,A61P 35/04 (2006.01) ,A61P 35/00 (2006.01) ,A61K 45/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
04
specific for metastasis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants:
IMMODULON THERAPEUTICS LIMITED [GB/GB]; 475 Salisbury House London Wall London Greater London EC2M 5QQ, GB
Inventors:
MARTYN, Glen; GB
KAMPINGA, Jakob; GB
BURTON, Graham; GB
DALGLEISH, Angus; GB
Agent:
GILL JENNINGS & EVERY LLP; The Broadgate Tower 20 Primrose Street London EC2A 2ES, GB
JAPPY, John; GB
Priority Data:
18179675.625.06.2018EP
Title (EN) CANCER THERAPY
(FR) THÉRAPIE ANTI-CANCÉREUSE
Abstract:
(EN) A non-viable, whole-cell Mycobacterium for use in the treatment, reduction, inhibition or control of one or more tumours in a checkpoint inhibitor refractory patient, wherein said checkpoint inhibitor refractory patient is intended to undergo checkpoint inhibition therapy simultaneously, separately or sequentially with administration of the Mycobacterium, and/or co-stimulatory checkpoint therapy, and optionally further comprising administering one or more additional anticancer treatments or agents.
(FR) L'invention concerne une mycobactérie non viable, à cellules entières, destinée à être utilisée dans le traitement, la réduction, l'inhibition ou la régulation d'une ou plusieurs tumeurs chez un patient réfractaire à un inhibiteur de points de contrôle, ledit patient réfractaire à un inhibiteur de points de contrôle étant destiné à subir une thérapie d'inhibition de points de contrôle simultanément, séparément ou successivement avec l'administration de la mycobactérie, et/ou une thérapie de points de contrôle co-stimulatrice, et consistant éventuellement en outre à administrer un ou plusieurs traitements ou agents anti-cancéreux supplémentaires.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)