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1. (WO2020002650) A FORMULATION
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2020/002650 International Application No.: PCT/EP2019/067428
Publication Date: 02.01.2020 International Filing Date: 28.06.2019
IPC:
A61K 9/08 (2006.01) ,A61K 9/00 (2006.01) ,A61K 47/10 (2017.01) ,A61K 47/26 (2006.01) ,A61K 38/19 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
Applicants:
TARGOVAX ASA [NO/NO]; Lilleakerveien 2C 0283 Oslo, NO
Inventors:
ERIKSEN, Jon Amund; NO
JONSBU, Einar; NO
IVERSEN, Berit; NO
Agent:
ARENDS, William Gerrit; GB
Priority Data:
18181026.829.06.2018EP
Title (EN) A FORMULATION
(FR) FORMULATION
Abstract:
(EN) There is disclosed a formulation comprising a GM-CSF protein having at least 60% sequence identity to the polypeptide sequence of SEQ ID NO: 2. The formulation comprises a stabiliser, wherein the stabiliser comprises a poloxamer present in an amount of 0.5-3.0wt%, excluding water. The formulation does not comprise more than 0.2wt%of human serum albumin or recombinant human albumin.
(FR) L'invention concerne une formulation comprenant une protéine GM-CSF ayant au moins 60% d'identité de séquence avec la séquence polypeptidique de SEQ ID NO: 2. La formulation comprend un stabilisant, le stabilisant comprenant un poloxamère présent en une quantité de 0,5 à 3,0 % en poids, à l'exclusion de l'eau. La formulation ne comprend pas plus de 0,2 % en poids d'albumine sérique humaine ou d'albumine humaine recombinante.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)