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1. WO2020002605 - FREEZING, DRYING AND/OR FREEZE-DRYING OF PRODUCT DOSE UNITS

Publication Number WO/2020/002605
Publication Date 02.01.2020
International Application No. PCT/EP2019/067333
International Filing Date 28.06.2019
IPC
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
26
DRYING
B
DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
5
Drying solid materials or objects by processes not involving the application of heat
04
by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
06
the process involving freezing
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
J
CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
3
Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
26
DRYING
B
DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
25
Details of general application not covered by group F26B21/ or F26B23/112
06
Chambers, containers, or receptacles
14
Chambers, containers, receptacles of simple construction
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
26
DRYING
B
DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
25
Details of general application not covered by group F26B21/ or F26B23/112
06
Chambers, containers, or receptacles
14
Chambers, containers, receptacles of simple construction
18
mainly open, e.g. dish, tray, pan
G PHYSICS
01
MEASURING; TESTING
K
MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
13
Adaptations of thermometers for specific purposes
F26B 5/06 (2006.01)
A61J 3/00 (2006.01)
F26B 25/14 (2006.01)
F26B 25/18 (2006.01)
G01K 13/00 (2006.01)
CPC
F26B 25/14
F26B 25/18
F26B 25/22
F26B 5/044
F26B 5/06
G01K 13/00
Applicants
  • UNIVERSITEIT GENT [BE/BE]; Sint-Pietersnieuwstraat 25 9000 Gent, BE
Inventors
  • DE BEER, Thomas; BE
  • CORVER, Jozef, Antonius, Willem, Maria; NL
  • VANBILLEMONT, Brecht; BE
  • REMON, Jean Paul; BE
Agents
  • HERTOGHE, Kris; BE
  • WAUTERS, Davy; BE
  • VAN BLADEL, Marc; BE
  • EGO, Christophe; BE
  • VAES, Peter; BE
Priority Data
18180796.729.06.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FREEZING, DRYING AND/OR FREEZE-DRYING OF PRODUCT DOSE UNITS
(FR) CONGÉLATION, SÉCHAGE ET/OU LYOPHILISATION D'UNITÉS DE DOSES DE PRODUIT
Abstract
(EN)
The invention relates to a device (1) for holding and monitoring a predetermined dose (4) of a product during a freezing, drying and/ or lyophilization process. The device comprises a mold (2) having a receptacle part (3) for containing the predetermined dose (4) of the product in direct contact with the receptacle part, a sensor (5), contacting the mold or integrated in the mold, for measuring a physical characteristic and/or quantity, and a transmitter (6) for transmitting the measured characteristic and/or quantity in the form of a sensor signal to a control unit for controlling a heating and/or cooling element (8,12,13), integrated in the device, for heating and/ or cooling a predetermined dose (4) of product during a freezing, drying and/or lyophilization process, in said lyophilization process. The invention relates in further aspects to a system and a method.
(FR)
L'invention concerne un dispositif (1) de maintien et de surveillance d'une dose prédéterminée (4) d'un produit lors d'un processus de congélation, de séchage et/ou de lyophilisation. Le dispositif comprend un moule (2) ayant une partie réceptacle (3) destinée à contenir la dose prédéterminée (4) du produit en contact direct avec la partie réceptacle, un capteur (5), en contact avec le moule ou intégrée dans le moule, destiné à la mesure d'une caractéristique et/ou d'une quantité physique, et un émetteur (6) destiné à émettre la caractéristique et/ou la grandeur mesurée sous la forme d'un signal de capteur à une unité de commande destinée à commander un élément de chauffage et/ou de refroidissement (8, 12, 13), intégré dans le dispositif, pour chauffer et/ou refroidir une dose prédéterminée (4) de produit pendant un processus de congélation, de séchage et/ou de lyophilisation, dans ledit procédé de lyophilisation. Selon d'autres aspects, l'invention se rapporte à un système et à un procédé.
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