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1. (WO2020001662) RARE CELL CAPTURE SYSTEM AND APPLICATION THEREOF
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2020/001662 International Application No.: PCT/CN2019/094629
Publication Date: 02.01.2020 International Filing Date: 03.07.2019
IPC:
C12M 1/00 (2006.01) ,C12N 5/09 (2010.01) ,A61M 1/36 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
09
Tumour cells
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1
Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36
Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
Applicants:
成都普瑞康生物科技有限公司 CHENGDU PRECISOME BIOTECHNOLOGY CO., LTD. [CN/CN]; 中国四川省成都市 高新区高朋大道科园三路4号火炬时代B区903 Huoju Times Building, Suit B-903 #4 Scientific Park 3rd Road, High Technology District Chengdu, Sichuan 610000, CN
四川大学 SICHUAN UNIVERSITY [CN/CN]; 中国四川省成都市 一环路南一段24号 No.24 South Section 1, Yihuan Road Chengdu, Sichuan 610015, CN
Inventors:
石虎兵 SHI, Hubing; CN
李燕雏 LI, Yanchu; CN
徐琪 XU, Qi; CN
孔祥菊 KONG, Xiangju; CN
王学焱 WANG, Xueyan; CN
韩赫文 HAN, Hewen; CN
Agent:
北京惠智天成知识产权代理事务所(特殊普通合伙) BEIJING HUI ZHI TIANCHENG INTELLECTUAL PROPERTY OFFICE (LLP); 中国北京市 海淀区安宁庄村南北方丝绸厂平房162号 No. 162, North Silk Factory South of Anning Village, Haidian District Beijing 100082, CN
Priority Data:
201810666625.X26.06.2018CN
Title (EN) RARE CELL CAPTURE SYSTEM AND APPLICATION THEREOF
(FR) SYSTÈME DE CAPTURE DE CELLULES RARES, ET SON APPLICATION
(ZH) 稀有细胞捕获系统及其应用
Abstract:
(EN) Disclosed are a rare cell capture system and an application thereof. The system comprises a fluid tube device, a circulation power apparatus device, a component capture device and an optional anticoagulant release device, the circulation power apparatus device and the component capture device being connected in series to a fluid circulation system via the fluid tube device to form an extracorporeal fluid circulation pathway, the component capture device comprising a microfluidic chip or a chipset. Also disclosed is a method for using the capture system to capture rare cells in blood. The system and the application thereof have the advantages of being large-capacity, in-line and low-haemolysis.
(FR) La présente invention concerne la détection de fluide corporel biologique et pathologique, et concerne en particulier un système de séparation d'un composant rare d'un échantillon de fluide corporel biologique, et une application dudit système. La présente invention concerne en outre un système pour séparer des cellules rares d'une population de cellules de sang total, et une application dudit système, en particulier un système à grande capacité, en ligne, à faible hémolyse pour collecter des cellules tumorales circulantes à partir du sang, et une application dudit système.
(ZH) 本发明公开了稀有细胞捕获系统及其应用,该系统包括流体管道设备,循环动力装置设备,组分捕获设备和任选的抗凝剂释放设备;其中该循环动力装置设备和组分捕获设备通过流体管道设备串联接入流体循环系统,形成体外流体循环通路;其中该组分捕获设备包括微流控芯片或芯片组。本发明还公开了使用所述捕获系统捕获血液中稀有细胞的方法。该系统及其应用具有大容量、在线式、低溶血性等优点。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)