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1. WO2020001592 - DIHYDROPYRIMIDINE DERIVATIVES AND USE THEREOF

Publication Number WO/2020/001592
Publication Date 02.01.2020
International Application No. PCT/CN2019/093578
International Filing Date 28.06.2019
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
417
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196
14
containing three or more hetero rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
14
containing three or more hetero rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
506
not condensed and containing further heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
C07D 417/14 (2006.01)
C07D 413/14 (2006.01)
A61K 31/506 (2006.01)
A61P 31/12 (2006.01)
CPC
A61K 31/506
A61P 31/12
C07D 413/14
C07D 417/14
Applicants
  • 河南天晟泰丰医药科技有限公司 HENAN TIANSHENG TAIFENG PHARMACEUTICAL TECHNOLOGY CO., LTD. [CN/CN]; 中国河南省郑州 航空港区建设路3号101室 Room 101, No. 3 Jianshe Road, Airport District Zhengzhou, Henan 451162, CN
Inventors
  • 沙薇 SHA, Wei; CN
Agents
  • 北京市柳沈律师事务所 LIU, SHEN & ASSOCIATES; 中国北京市 海淀区彩和坊路10号1号楼10层 10th Floor, Building 1, 10 Caihefang Road Haidian District, Beijing 100080, CN
Priority Data
201810691836.928.06.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) DIHYDROPYRIMIDINE DERIVATIVES AND USE THEREOF
(FR) DÉRIVÉS DE DIHYDROPYRIMIDINE ET LEUR UTILISATION
(ZH) 二氢嘧啶衍生物及其用途
Abstract
(EN)
The present invention relates to dihydropyrimidine derivatives as represented by general formula (I), which are applicable to the treatment and prevention of hepatitis B virus infection. The invention further relates to pharmaceutical compositions containing a compound as represented by formula (I), and use thereof for the treatment and prevention of hepatitis B virus infection.
(FR)
La présente invention concerne des dérivés de dihydropyrimidine tels que représentés par la formule générale (I), qui sont applicables au traitement et à la prévention d'une infection par le virus de l'hépatite B. L'invention concerne en outre des compositions pharmaceutiques contenant un composé tel que représenté par la formule (I), et leur utilisation pour le traitement et la prévention d'une infection par le virus de l'hépatite B.
(ZH)
本发明涉及通式(I)的二氢嘧啶类衍生物,它们可用于治疗和预防乙型肝炎病毒感染。本发明还涉及含有通式(I)化合物的药物组合物,及其用于治疗和预防乙型肝炎病毒感染的用途。
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