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1. (WO2020000457) GRNA TARGETING SEQUENCE THAT SPECIFICALLY TARGETS HUMAN KAT13D GENE AND USE THEREOF
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2020/000457 International Application No.: PCT/CN2018/093867
Publication Date: 02.01.2020 International Filing Date: 29.06.2018
IPC:
C12N 15/113 (2010.01) ,C12N 15/85 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
113
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
Applicants:
深圳市博奥康生物科技有限公司 SHENZHEN BIOCAN TECHNOLOGIES CO., LTD. [CN/CN]; 中国广东省深圳市 南山区西丽街道珠光路134号珠光创新科技园1栋509室 毛吉炎 MAO, Jiyan Room 509, Building 1, Zhuguang Innovation Park No.134 Zhuguang Road, Xilii Street, Nanshan District Shenzhen, Guangdong 518055, CN
Inventors:
毛吉炎 MAO, Jiyan; CN
Priority Data:
Title (EN) GRNA TARGETING SEQUENCE THAT SPECIFICALLY TARGETS HUMAN KAT13D GENE AND USE THEREOF
(FR) SÉQUENCE DE CIBLAGE D'ARNG QUI CIBLE SPÉCIFIQUEMENT LE GÈNE KAT13D HUMAIN ET SON UTILISATION
(ZH) 一种特异靶向人KAT13D基因的gRNA导向序列及其应用
Abstract:
(EN) Disclosed are a gRNA targeting sequence that specifically targets the human KAT13D gene and the use thereof, wherein the nucleotide sequence of the gRNA targeting sequence is 5'-CAAACGCCAGCGGCGGTGAC-3'. The knockout of the KAT13D gene is achieved by introducing the gRNA and CRISPR system into target cells using the Cas9 vector.
(FR) L'invention concerne une séquence de ciblage d'ARNg qui cible spécifiquement le gène KAT13D humain et son utilisation, la séquence nucléotidique de la séquence de ciblage d'ARNg étant 5'-CAAACGCCAGCGGCGGTGAC-3'. L'inactivation du gène KAT13D est obtenue par introduction de l'ARNg et du système CRISPR dans des cellules cibles à l'aide du vecteur Cas9.
(ZH) 一种特异靶向人KAT13D基因的gRNA导向序列及其应用,该gRNA导向序列的核苷酸序列为5'-CAAACGCCAGCGGCGGTGAC-3'。利用Cas9载体将该gRNA以及CRISPR系统引入目标细胞后,实现KAT13D基因的敲除。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)