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1. WO2019229114 - MILD COMPOSITION FOR USE IN TOPICAL TREATMENT OF SKIN AND NAIL DISORDERS CAUSED BY VIRUS AND FUNGUS

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Claims

1. A topical composition comprising: an alpha hydroxy acid selected from the group consisting of lactic acid, malic acid, and glycolic acid, and combinations thereof in a total amount of from 50 to 80 % by weight; 0.1 to 10 % by weight of methyl salicylate; and, a wa ter soluble zinc salt in an amount of from 0.2 to 4% by weight of the formulation calculated as Zn.

2. The composition of claim 1, further comprising a solubiliser in an amount effective for solubilizing the methyl salicylate in the formulation.

3. The composition of claim 2, wherein said solubiliser is an ethoxylated fatty alcohol.

4. The composition of any one of the preceding claims, wherein the the total amount of the alpha hydroxy acid is within the range of 50-70 % by weight.

5. The composition of any one of the preceding claims, wherein the amount of methyl salicylate is 0.2-10% by weight.

6. The composition of any one of the preceding claims, wherein the alpha hydroxy acid is glycolic acid.

7. The composition of any one of the preceding claims, wherein the water soluble zinc salt is one or more members selected from the group consisting of zinc sulphate, zinc chlo ride, zinc acetate, zinc glycolate, zinc gluconate, zinc carbonate, zinc oxide, zinc oleate, zinc stearate, zinc propionate, zinc salicylate, zinc lactate, zinc coceth sulphate, zinc citrate, zinc ascorbate and zinc glutamate.

8. The composition of claim 7, wherein the water soluble zinc salt is zinc sulphate.

9. The composition according to any one of the preceding claims, wherein the amount by weight of zinc is from 1.0 to 2.5%, glycolic acid is from 55 to 65 %, and methyl salicylate is from 2 to 5 %, respectively.

10. A kit comprising a container holding the composition of any one of claims 1-9, and an applicator for topical application of the composition.

11. An applicator comprising a felt tip, a brush tip, or a roller ball tip attached to a con-tainer holding the composition of any one of claims 1-9, from which container the composi-tion can be delivered to the tip of the applicator.

12. A pen containing the composition of any one of claims 1-9 for the topical administra tion of the composition from a tip of the pen to an affected skin area for the treatment of warts.

13. A method of treating warts wherein the composition of any one of claims 1-9 is ap plied to an affected skin area of a subject.

14. A method of treating of treating fungal infections of the toenails or fingernails, wherein the inventive composition of any one of claims 1-9 is applied topically to an area of affected nail.