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1. WO2019223519 - TUMOR MARKER, METHYLATION DETECTION REAGENT, KIT AND APPLICATION THEREOF

Publication Number WO/2019/223519
Publication Date 28.11.2019
International Application No. PCT/CN2019/085587
International Filing Date 05.05.2019
IPC
C12Q 1/6886 2018.1
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C12Q 2600/154
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2600Oligonucleotides characterized by their use
154Methylation markers
Applicants
  • 广州市康立明生物科技有限责任公司 CREATIVE BIOSCIENCES (GUANGZHOU) CO., LTD. [CN]/[CN]
Inventors
  • 刘相林 LIU, Xianglin
  • 赵荣淞 ZHAO, Rongsong
  • 邹鸿志 ZOU, Hongzhi
Agents
  • 北京市万慧达律师事务所 BEIJING WANHUIDA LAW FIRM
Priority Data
201810495761.722.05.2018CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) TUMOR MARKER, METHYLATION DETECTION REAGENT, KIT AND APPLICATION THEREOF
(FR) MARQUEUR TUMORAL, RÉACTIF DE DÉTECTION DE MÉTHYLATION, KIT ET APPLICATION DE CEUX-CI
(ZH) 肿瘤标志物、甲基化检测试剂、试剂盒及其应用
Abstract
(EN) Disclosed in the present invention are a tumor marker, a methylation detection reagent, a kit and an application thereof. A colorectal cancer specimen may be distinguished from a normal human fecal specimen by means of detecting the methylation level of a TMEM240 gene promoter region. The present invention detects colorectal cancer using a methylation detection reagent containing the gene.
(FR) La présente invention concerne un marqueur tumoral, un réactif de détection de méthylation, un kit et une application de ceux-ci. Un échantillon de cancer colorectal peut être distingué d'un échantillon fécal humain normal au moyen de la détection du niveau de méthylation d'une région de promoteur de gène TMEM240. La présente invention détecte un cancer colorectal à l'aide d'un réactif de détection de méthylation contenant le gène.
(ZH) 本发明公开了肿瘤标志物、甲基化检测试剂、试剂盒及其应用。通过检测TMEM240基因启动子区的甲基化水平可以从正常人的粪便标本中区分出结直肠癌标本。本发明利用含有该基因的甲基化检测试剂来检测结直肠癌。
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