WO2019215280 GYCOMODULE MOTIFS AND USES THEREOF

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Publication Number WO/2019/215280

Publication Date 14.11.2019

International Application No. PCT/EP2019/061916

International Filing Date 09.05.2019

IPC

CPC

Applicants

GAT BIOSCIENCES, S.L. [ES]/[ES]

Inventors

DURANY TURK, Olga
SEGURA DE YEBRA, Jordi
MERCADÉ ROCA, Jaume
LÓPEZ CERRO, María Teresa
LÓPEZ PAZ, Cristina

Agents

ABG INTELLECTUAL PROPERTY LAW, S.L.

Priority Data

18382319.4

09.05.2018

Publication Language English (en)

Filing Language English (EN)

Designated States

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Title

(EN) GYCOMODULE MOTIFS AND USES THEREOF

(FR) MOTIFS DE GLYCOMODULES ET LEURS UTILISATIONS

Abstract

(EN) The present invention relatesto a nucleotide sequence encoding a glycomodule motifhaving a sequence selected from the group consisting of SEQ IDNO 1, SEQ ID NO 2, SEQ IDNO 3, SEQ IDNO 4, SEQ IDNO 5 and a functionally equivalent variant thereof. In addition, the invention relates to an expression cassette comprising at least one nucleotide sequence encoding a glycomodule motif of the invention. The invention also relates to a vector and host cell and to a method for expressing a protein of interest.

(FR) La présente invention concerne une séquence nucléotidique codant pour un motif de glycomodule ayant une séquence choisie parmi le groupe constitué par SEQ IDNO 1, SEQ ID NO 2, SEQ IDNO 3, SEQ IDNO 4, SEQ IDNO 5 et un variant fonctionnellement équivalent associé. De plus, l'invention concerne une cassette d'expression comprenant au moins une séquence nucléotidique codant pour un motif glycomodule de l'invention. L'invention concerne également un vecteur et une cellule hôte et un procédé d'expression d'une protéine d'intérêt.

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology
63	Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79	Vectors or expression systems specially adapted for eukaryotic hosts

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21	Preparation of peptides or proteins

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology
63	Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79	Vectors or expression systems specially adapted for eukaryotic hosts

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21	Preparation of peptides or proteins

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology
63	Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79	Vectors or expression systems specially adapted for eukaryotic hosts

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