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1. WO2019198013 - BLOOD-FREE DIET FOR REARING MALARIA MOSQUITO VECTORS

Publication Number WO/2019/198013
Publication Date 17.10.2019
International Application No. PCT/IB2019/052967
International Filing Date 10.04.2019
IPC
C07K 14/72 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
72for hormones
A01K 67/033 2006.01
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
033Rearing or breeding invertebrates; New breeds of invertebrates
A23K 50/90 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
KFEEDING-STUFFS SPECIALLY ADAPTED FOR ANIMALS; METHODS SPECIALLY ADAPTED FOR PRODUCTION THEREOF
50Feeding-stuffs specially adapted for particular animals
90for insects, e.g. bees or silkworms
CPC
A01K 67/033
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
033Rearing or breeding invertebrates; New breeds of invertebrates
A23K 20/147
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
KFODDER
20Accessory food factors for animal feeding-stuffs
10Organic substances
142Amino acids; Derivatives thereof
147Polymeric derivatives, e.g. peptides or proteins
A23K 50/90
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
KFODDER
50Feeding-stuffs specially adapted for particular animals
90for insects, e.g. bees or silkworms
C07K 14/72
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
72for hormones
C07K 14/723
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
72for hormones
723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
Applicants
  • UNIVERSIDADE NOVA DE LISBOA-INSTITUTO DE HIGIENE E MEDICINA TROPICAL (IHMT-NOVA) [PT]/[PT]
  • CENTRO DE CIENCIAS DO MAR DO ALGARVE [PT]/[PT]
Inventors
  • SILVEIRA, Henrique
  • MARQUES, Maria
  • CARDOSO, João
  • FÉLIX, Rute
  • POWER, Deborah
Agents
  • GATA, Ligia
Priority Data
11068411.04.2018PT
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BLOOD-FREE DIET FOR REARING MALARIA MOSQUITO VECTORS
(FR) RÉGIME EXEMPT DE SANG POUR L'ÉLEVAGE DE MOUSTIQUES VECTEURS DU PALUDISME
Abstract
(EN)
The present invention relates to blood-free-diets for malaria mosquito vectors that support ovarian development, egg maturation and fertility, as well as low progeny larval mortality, and normal development of offspring into adult mosquitoes. The formulated diets comprise supplements of physiological concentrations of several different human GPCR ligands and shown to be an effective artificial meal, free of blood that mimics a vertebrate blood meal and represents an important advance for the sustainability of Anopheles mosquito rearing in captivity. The present invention is in the domain of genetic engineering, parasitology, entomology medicine, pharmaceuticals and diagnose.
(FR)
La présente invention concerne des régimes exempts de sang pour des moustiques vecteurs du paludisme qui favorisent le développement ovarien, la maturation et la fertilité des œufs, ainsi qu'une faible mortalité larvaire des descendants et le développement normal de la descendance chez des moustiques adultes. Les régimes formulés comprennent des suppléments de concentrations physiologiques de plusieurs ligands GPCR humains différents et sont susceptibles d'être un repas artificiel efficace, exempt de sang qui imite un repas sanguin de vertébré et représente une avance importante pour la durabilité de l'élevage de moustiques Anopheles en captivité. La présente invention se rapporte au domaine du génie génétique, de la parasitologie, de la médecine d'entomologie, de produits pharmaceutiques et de diagnostic.
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