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1. WO2019186084 - ANTI-COMPLEMENT HISTONES

Publication Number WO/2019/186084
Publication Date 03.10.2019
International Application No. PCT/GB2018/050789
International Filing Date 26.03.2018
IPC
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
Applicants
  • THE UNIVERSITY OF LIVERPOOL [GB]/[GB]
Inventors
  • ABRAMS, Simon Timothy
  • TOH, Cheng Hock
  • WANG, Guozheng
Agents
  • HGF LIMITED
Priority Data
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-COMPLEMENT HISTONES
(FR) HISTONES ANTI-COMPLÉMENT
Abstract
(EN)
The invention relates to histone proteins and modified histone proteins for use in inhibiting the activity of complement, which also includes the medical use of modified histones in the treatment or prevention of diseases associated with enhanced complement activity. The invention further relates to modified histone proteins themselves, and to non-medical uses of histones for inhibiting complement activity in components of cell culture media.
(FR)
L'invention concerne des protéines d'histone et des protéines d'histone modifiées destinées à être utilisées pour inhiber l'activité du complément, comprenant également l'utilisation médicale d'histones modifiées dans le traitement ou la prévention de maladies associées à une activité du complément améliorée. L'invention concerne en outre des protéines d'histone modifiées, et des utilisations non médicales d'histones pour inhiber l'activité du complément dans des composants de milieux de culture cellulaire.
Latest bibliographic data on file with the International Bureau