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1. WO2019145401 - METHOD AND APPARATUS

Publication Number WO/2019/145401
Publication Date 01.08.2019
International Application No. PCT/EP2019/051713
International Filing Date 24.01.2019
IPC
A61K 9/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
16Agglomerates; Granulates; Microbeadlets
A61K 31/167 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
167having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
CPC
A61K 31/167
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
167having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 9/1688
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
16Agglomerates; Granulates; Microbeadlets ; ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
1682Processes
1688resulting in pure drug agglomerate optionally containing up to 5% of excipient
Applicants
  • UNIVERSITY OF LIMERICK [IE]/[IE]
Inventors
  • ALBADARIN, Ahmad B.
  • WALKER, Gavin
  • ZEGLINSKI, Jacek
Agents
  • APPLEYARD LEES IP LLP
Priority Data
1801415.929.01.2018GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD AND APPARATUS
(FR) PROCÉDÉ ET APPAREIL
Abstract
(EN)
A method of processing an active pharmaceutical ingredient,the method comprising passing a precursor composition comprising the active pharmaceutical ingredient and a solvent through a twin screw extruder wherein the twin screw extruder is heated at ambient pressure.
(FR)
L'invention concerne un procédé de traitement d'un ingrédient pharmaceutique actif, le procédé comprenant le passage d'une composition précurseur comprenant l'ingrédient pharmaceutique actif et un solvant à travers une extrudeuse à double vis, l'extrudeuse à double vis étant chauffée à pression ambiante.
Also published as
EP2019701826
Latest bibliographic data on file with the International Bureau