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1. WO2019113312 - ANTICANCER COMPOUND PROCESS

Publication Number WO/2019/113312
Publication Date 13.06.2019
International Application No. PCT/US2018/064244
International Filing Date 06.12.2018
IPC
A61K 31/4192 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41921,2,3-Triazoles
C07C 43/20 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
43Ethers; Compounds having groups, groups or groups
02Ethers
20having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
C07C 49/76 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
49Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
76Ketones containing a keto group bound to a six-membered aromatic ring
C07C 49/788 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
49Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
76Ketones containing a keto group bound to a six-membered aromatic ring
782polycyclic
788with keto groups bound to a condensed ring system
CPC
A61K 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
A61K 31/4192
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
41921,2,3-Triazoles
C07B 2200/07
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
2200Indexing scheme relating to specific properties of organic compounds
07Optical isomers
C07B 57/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
57Separation of optically-active compounds
C07C 41/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
41Preparation of ethers; Preparation of compounds having groups, groups or groups
01Preparation of ethers
18by reactions not forming ether-oxygen bonds
C07C 41/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
41Preparation of ethers; Preparation of compounds having groups, groups or groups
01Preparation of ethers
18by reactions not forming ether-oxygen bonds
30by increasing the number of carbon atoms, e.g. by oligomerisation
Applicants
  • INNOCRIN PHARMACEUTICALS, INC.
Inventors
  • SHARP, Matthew
  • WIRTH, David, Dale
  • HOEKSTRA, William, J.
  • RAFFERTY, Stephen, W.
  • BINDL, Martin, F.
Agents
  • HSI, Jeffrey, D.
Priority Data
62/596,47308.12.2017US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ANTICANCER COMPOUND PROCESS
(FR) PROCÉDÉ DE PRÉPARATION D'UN COMPOSÉ ANTICANCÉREUX
Abstract
(EN) The present invention relates to a process for preparing compound 1 that useful as an anticancer agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
(FR) La présente invention concerne un procédé de préparation du composé 1 qui est utile en tant qu'agent anticancéreux. L'invention vise en particulier à fournir une nouvelle méthodologie de préparation du composé 1 et de dérivés substitués de celui-ci.
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