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1. WO2019095080 - SYSTEM AND METHOD FOR QUANTIFYING THE PRESENCE OF CHEMICALS AND/OR PHYSICAL CONDITIONS IN OCULAR TISSUES

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Publication Number WO/2019/095080
Publication Date 23.05.2019
International Application No. PCT/CA2018/051477
International Filing Date 20.11.2018
IPC
A61B 3/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/18 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
18Arrangement of plural eye-testing or -examining apparatus
C09K 11/07 2006.1
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
KMATERIALS FOR APPLICATIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
11Luminescent, e.g. electroluminescent, chemiluminescent, materials
06containing organic luminescent materials
07having chemically-interreactive components, e.g. reactive chemiluminescent compositions
G02C 7/04 2006.1
GPHYSICS
02OPTICS
CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
7Optical parts
02Lenses; Lens systems
04Contact lenses for the eyes
CPC
A61B 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
A61B 3/145
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
14Arrangements specially adapted for eye photography
145by video means
A61K 49/0013
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
C09K 11/07
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
11Luminescent, e.g. electroluminescent, chemiluminescent materials
06containing organic luminescent materials
07having chemically interreactive components, e.g. reactive chemiluminescent compositions
C09K 2211/1007
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
2211Chemical nature of organic luminescent or tenebrescent compounds
10Non-macromolecular compounds
1003Carbocyclic compounds
1007Non-condensed systems
C09K 2211/1011
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
2211Chemical nature of organic luminescent or tenebrescent compounds
10Non-macromolecular compounds
1003Carbocyclic compounds
1011Condensed systems
Applicants
  • OPTIGGX INC. [CA]/[CA]
Inventors
  • PACAL, Marek
  • SIVAK, Jeremy Michael
  • WILHELM, Stefan
  • FONN, Desmond
Agents
  • DLA PIPER (CANADA) LLP
Priority Data
62/588,53320.11.2017US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) SYSTEM AND METHOD FOR QUANTIFYING THE PRESENCE OF CHEMICALS AND/OR PHYSICAL CONDITIONS IN OCULAR TISSUES
(FR) SYSTÈME ET PROCÉDÉ DE QUANTIFICATION DE LA PRÉSENCE DE PRODUITS CHIMIQUES ET/OU DE CONDITIONS PHYSIQUES DANS DES TISSUS OCULAIRES
front page image
Abstract
(EN) A system for quantifying the presence of at least one chemical and/or a physical condition in ocular tissues is provided. The system uses a membrane having at least one photo-reactive chemical- and/or physical condition-sensing indicator dye and a photo- reactive reference dye wherein both the photo-reactive chemical- and/or physical condition-sensing indicator dye and the photo-reactive reference dye are responsive to the same wavelength of an excitation light source but emit different wavelengths of light in a light spectrum. An optical data detector receives the emitted light and a processor splits the data into two or more colours of the light spectrum and measures the intensity of the two or more colours. The colour intensity belonging to the emitted light from the chemical- and/or physical condition-sensing indicator dye is compared to the colour intensity of the light emitted from the reference dye and the amount of chemical present and/or the extent of physical condition is ratiometrically determined therefrom.
(FR) L'invention concerne un système permettant de quantifier la présence d'au moins un produit chimique et/ou d'une condition physique dans des tissus oculaires. Le système utilise une membrane ayant au moins un colorant indicateur de détection de produit chimique et/ou condition physique photo-réactif et un colorant de référence photo-réactif, le colorant indicateur de détection de produit chimique et/ou condition physique photo-réactif et le colorant de référence photo-réactif étant sensibles à la même longueur d'onde d'une source de lumière d'excitation mais émettant différentes longueurs d'onde de lumière dans un spectre de lumière. Un détecteur de données optique reçoit la lumière émise et un processeur divise les données en deux couleurs ou plus du spectre de lumière et mesure l'intensité des deux couleurs ou plus. L'intensité de couleur appartenant à la lumière émise par le colorant indicateur de détection de produit chimique et/ou condition physique est comparée à l'intensité de couleur de la lumière émise par le colorant de référence et la quantité de produit chimique présent et/ou l'étendue de condition physique est déterminée de manière ratiométrique à partir de celle-ci.
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