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1. (WO2019088095) ANALGESIC AND USE THEREOF
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/088095 International Application No.: PCT/JP2018/040319
Publication Date: 09.05.2019 International Filing Date: 30.10.2018
IPC:
A61K 45/00 (2006.01) ,A61P 25/04 (2006.01) ,A61P 43/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
04
Centrally acting analgesics, e.g. opioids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants:
国立大学法人九州大学 KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION [JP/JP]; 福岡県福岡市西区元岡744 744, Motooka, Nishi-ku, Fukuoka-shi, Fukuoka 8190395, JP
Inventors:
津田 誠 TSUDA Makoto; JP
高露 雄太 KOHRO Yuta; JP
Agent:
棚井 澄雄 TANAI Sumio; JP
松沼 泰史 MATSUNUMA Yasushi; JP
及川 周 OIKAWA Shu; JP
飯田 雅人 IIDA Masato; JP
Priority Data:
2017-21319602.11.2017JP
2018-01865305.02.2018JP
Title (EN) ANALGESIC AND USE THEREOF
(FR) ANALGÉSIQUE ET SON UTILISATION
(JA) 鎮痛剤及びその使用
Abstract:
(EN) The present invention provides: an analgesic that contains, as an active ingredient, a substance that inhibits a signal from an adrenaline α1 receptor of astrocyte; and an analgesic screening method characterized by selecting a substance that inhibits a signal from the adrenaline α1 receptor of astrocyte.
(FR) La présente invention concerne : un analgésique qui contient, en tant que principe actif, une substance qui inhibe le signal provenant des récepteurs α1 adrénergiques des astrocytes ; et une méthode de criblage d'analgésiques caractérisée par le fait qu'elle sélectionne des substances qui inhibent un signal provenant des récepteurs α1 adrénergiques des astrocytes.
(JA) アストロサイトのアドレナリンα1受容体からのシグナルを阻害する物質を有効成分として含有する鎮痛剤、及びアストロサイトのアドレナリンα1受容体からのシグナルを阻害する物質を選択することを特徴とする、鎮痛剤のスクリーニング方法。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)