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1. WO2019079857 - METHOD AND DEVICE FOR ACOUSTICALLY MEDIATED INTRACELLULAR DELIVERY

Publication Number WO/2019/079857
Publication Date 02.05.2019
International Application No. PCT/AU2018/051154
International Filing Date 26.10.2018
IPC
B06B 1/06 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
06GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
BGENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
1Processes or apparatus for generating mechanical vibrations of infrasonic, sonic or ultrasonic frequency
02making use of electrical energy
06operating with piezo-electric effect or with electrostriction
A61M 11/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
11Sprayers or atomisers specially adapted for therapeutic purposes
CPC
A61K 9/0009
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
0009involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
B06B 1/06
BPERFORMING OPERATIONS; TRANSPORTING
06GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
BMETHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, ; e.g.; FOR PERFORMING MECHANICAL WORK IN GENERAL
1Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
02making use of electrical energy
06operating with piezo-electric effect or with electrostriction
B82Y 5/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
5Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
C12N 2521/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2521Culture process characterised by the use of hydrostatic pressure, flow or shear forces
10Sound, e.g. ultrasounds
C12N 5/0068
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
0068General culture methods using substrates
Applicants
  • ROYAL MELBOURNE INSTITUTE OF TECHNOLOGY [AU]/[AU]
Inventors
  • RAMESAN, Shwathy
  • REZK, Amgad
  • YEO, Leslie
Agents
  • FAL PATENTS PTY LTD
Priority Data
201790433326.10.2017AU
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD AND DEVICE FOR ACOUSTICALLY MEDIATED INTRACELLULAR DELIVERY
(FR) PROCÉDÉ ET DISPOSITIF DE DISTRIBUTION INTRACELLULAIRE À MÉDIATION ACOUSTIQUE
Abstract
(EN)
An intracellular delivery device (1) including, a piezoelectric substrate (3) having a working surface (8), at least one interdigitated transducer (5) located on and in contact with the working surface (8), and a receptacle (11) located on the working surface for accommodating cells to be targeted for intracellular delivery therein, wherein an alternating signal applied to the interdigitated transducer generates acoustic wave energy through the piezoelectric substrate that can be transferred to the accommodated cells.
(FR)
L'invention concerne un dispositif de distribution intracellulaire (1) comprenant un substrat piézoélectrique (3) comportant une surface de travail (8), au moins un transducteur interdigité (5) situé sur la surface de travail (8) et en contact avec celle-ci, ainsi qu'un réceptacle (11) situé sur la surface de travail pour recevoir des cellules à cibler pour une distribution intracellulaire, un signal alternatif appliqué sur le transducteur interdigité générant une énergie d'ondes acoustiques à travers le substrat piézoélectrique qui peut être transférée aux cellules reçues.
Also published as
Latest bibliographic data on file with the International Bureau