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1. (WO2019074954) SELECTION BIOMARKERS FOR PATIENT STRATIFICATION IN BODILY FLUIDS AND APPLYING PRECISION MEDICINE THROUGH NOVEL DIAGNOSTIC BIOMARKERS
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/074954 International Application No.: PCT/US2018/055059
Publication Date: 18.04.2019 International Filing Date: 09.10.2018
IPC:
G01N 33/68 (2006.01) ,G01N 33/72 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
72
involving blood pigments, e.g. hemoglobin, bilirubin
Applicants:
LIFESTORY HEALTH, INC. [US/US]; 285 Harvard Street, #363 Brookline, Massachusetts 02446, US
Inventors:
VILLARREAL, Anna; US
Agent:
CONNARN, Kristin A.; US
Priority Data:
62/569,99809.10.2017US
Title (EN) SELECTION BIOMARKERS FOR PATIENT STRATIFICATION IN BODILY FLUIDS AND APPLYING PRECISION MEDICINE THROUGH NOVEL DIAGNOSTIC BIOMARKERS
(FR) BIOMARQUEURS DE SÉLECTION DANS DES LIQUIDES CORPORELS POUR LA STRATIFICATION DES PATIENTS ET APPLICATION D'UN MÉDICAMENT DE PRÉCISION PAR L'INTERMÉDIAIRE DE NOUVEAUX BIOMARQUEURS DE DIAGNOSTIC
Abstract:
(EN) The present invention relates to, in part, methods of improved healthcare in female subjects that, for example, rely on menstrual fluid sampling for applying selection biomarkers. The invention provides a method for evaluating one or more disease- or health-related biomarkers in a female subject, comprising: (a) obtaining a sample of the female subject's menstrual fluid; (b) measuring the presence, absence, or level of one or more disease- or health-related biomarkers in the sample; and (c) repeating with subsequent menstrual fluid. Provided herein is a method of stratifying human female subject, comprising obtaining a sample of the female subject's menstrual fluid; separating proteins of the menstrual fluid; measuring the level of glycation of the hemoglobin subunit alpha in the sample; and assigning female subject to a category.
(FR) La présente invention concerne, en partie, des méthodes de soin de santé améliorés pour des patientes qui, par exemple, reposent sur l'échantillonnage du fluide menstruel pour appliquer des biomarqueurs de sélection. L'invention concerne un procédé d'évaluation d'un ou de plusieurs biomarqueurs associés à une maladie ou à la santé chez une patiente, comprenant : (a) obtenir un échantillon du fluide menstruel de la patiente; (b) mesurer la présence, l'absence ou le taux d'un ou de plusieurs biomarqueurs associés à une maladie ou à la santé dans l'échantillon; et (c) répéter avec un fluide menstruel ultérieur. La présente invention concerne un procédé de stratification d'une patiente humaine, consistant à obtenir un échantillon du fluide menstruel de la patiente; séparer les protéines du fluide menstruel; mesurer le taux de glycation de la sous-unité alpha de l'hémoglobine dans l'échantillon; et attribuer une patiente à une catégorie.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)