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1. (WO2019067966) PERFUSION APPARATUS FOR USE IN BIOREACTOR SYSTEMS
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Pub. No.: WO/2019/067966 International Application No.: PCT/US2018/053526
Publication Date: 04.04.2019 International Filing Date: 28.09.2018
IPC:
C12M 1/00 (2006.01) ,C12M 1/26 (2006.01) ,C12M 1/12 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
26
Inoculator or sampler
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
12
with sterilisation, filtration, or dialysis means
Applicants:
LEVINSON, Yonatan [US/US]; CH (US)
ABRAHAM, Eytan [US/US]; CH (US)
GUPTA, Siddharth [US/US]; CH (US)
LONZA LTD. [CH/CH]; Lonzastrasse 3930 Visp, CH
Inventors:
LEVINSON, Yonatan; CH
ABRAHAM, Eytan; CH
GUPTA, Siddharth; CH
Agent:
CASSIDY, Timothy A.; US
Priority Data:
62/565,18729.09.2017US
Title (EN) PERFUSION APPARATUS FOR USE IN BIOREACTOR SYSTEMS
(FR) APPAREIL DE PERFUSION DESTINÉ À ÊTRE UTILISÉ DANS DES SYSTÈMES DE BIORÉACTEUR
Abstract:
(EN) A perfusion apparatus as disclosed for withdrawing a fluid medium from a bioreactor during the growth of a cell culture on microcarriers within the bioreactor. Also disclosed is a method for culturing cells in a bioreactor contained on microcarriers. The perfusion apparatus includes a hollow tubular member attached to a filter member. The filter member has a pore size and volume capable of withdrawing a fluid medium at a relatively high flow rate from the bioreactor.
(FR) L'invention concerne un appareil de perfusion destiné à soutirer un milieu fluide d'un bioréacteur pendant la croissance d'une culture cellulaire sur des microsupports au sein du bioréacteur. L'invention concerne également un procédé de culture cellulaire dans un bioréacteur contenu sur des microsupports. L'appareil de perfusion comprend un élément tubulaire creux fixé à un élément de filtre. L'élément de filtre présente une taille et un volume de pores permettant de soutirer un milieu fluide à un débit relativement élevé à partir du bioréacteur.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)