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1. (WO2019067961) NOVEL SALTS
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Pub. No.: WO/2019/067961 International Application No.: PCT/US2018/053520
Publication Date: 04.04.2019 International Filing Date: 28.09.2018
IPC:
A61K 31/407 (2006.01) ,A61P 25/00 (2006.01) ,C07D 487/10 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
407
condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
10
Spiro-condensed systems
Applicants:
BIOGEN INC. [US/US]; 225 Binney Street Cambridge, MA 02142, US
Inventors:
GIBLIN, Gerard, M.P.; US
MACPHERSON, David, T.; US
WILLIAMS, Michael; US
WITTY, David, R.; US
NORTHEN, Julian; US
VASUDEVAN, Kalyan; US
Agent:
HALSTEAD, David, P.; US
ABELLEIRA, Susan, A.; US
BROW, Willam, E.; US
BLOUNT, Jennifer, V.; US
AKHIEZER, Alexander; US
Priority Data:
62/564,74428.09.2017US
Title (EN) NOVEL SALTS
(FR) NOUVEAUX SELS
Abstract:
(EN) The invention relates to novel salts of 7-methyl-2-[4-methyl-6-[4-(trifluoromethyl)- phenyl]pyrimidin-2-yl]-1,7-diazaspiro[4.4]nonan-6-one, to compositions containing said salts and to the use of said salts in treating diseases and conditions mediated by modulation of voltage-gated sodium channels.
(FR) L'invention concerne de nouveaux sels de 7-méthyl-2-[4-méthyl-6-[4- (trifluorométhyl)-phényl] pyrimidin-2-yl] -1,7-diazaspiro [4,4] nonan-6-one, des compositions contenant lesdits sels et l'utilisation desdits sels dans le traitement de maladies et d'états pathologiques médiés par la modulation de canaux sodiques voltage-dépendants.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)