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1. (WO2019067913) COMPOSITIONS AND METHODS OF TREATING CANCER
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Pub. No.: WO/2019/067913 International Application No.: PCT/US2018/053443
Publication Date: 04.04.2019 International Filing Date: 28.09.2018
IPC:
A61K 31/4709 (2006.01) ,A61K 31/5377 (2006.01) ,A61P 13/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
4709
Non-condensed quinolines containing further heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
535
having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
5375
1,4-Oxazines, e.g. morpholine
5377
not condensed and containing further heterocyclic rings, e.g. timolol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13
Drugs for disorders of the urinary system
12
of the kidneys
Applicants:
BRISTOL-MYERS SQUIBB COMPANY [US/US]; Route 206 & Province Line Road Princeton, NJ 08543, US
Inventors:
BASCIANO, Paul Andrew; US
WALKER, Justine Kamilah; US
PHILLIPS, Penny E.; US
ZHU, Li; US
BERNSTEIN, Steven H.; US
CASSIDY, James; US
SIMONSEN, Katy Lynn; US
AZRILEVICH, Alexander; US
SRIVASTAVA, Shivani; US
Agent:
LODISE, Stephanie A.; US
GORDON, Laura, R.; US
Priority Data:
62/565,81929.09.2017US
62/569,76609.10.2017US
62/580,21901.11.2017US
62/609,21021.12.2017US
62/642,71114.03.2018US
62/678,49031.05.2018US
Title (EN) COMPOSITIONS AND METHODS OF TREATING CANCER
(FR) COMPOSITIONS ET MÉTHODES DE TRAITEMENT DU CANCER
Abstract:
(EN) The disclosure is directed to methods of treating cancer in subjects with a combination of a monoclonal antibody and (R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide, or a salt thereof.
(FR) L'invention concerne des méthodes de traitement du cancer chez des sujets avec une combinaison d'un anticorps monoclonal et de (R)-N-(4-chlorophényl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide, ou d'un sel de celui-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)