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1. (WO2019067684) SWITCHABLE LOW VOLTAGE ELECTROCHEMICAL SENSING FOR INTERFERING SPECIES REJECTION
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Pub. No.: WO/2019/067684 International Application No.: PCT/US2018/053068
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
G01N 27/327 (2006.01) ,A61B 5/145 (2006.01) ,C12Q 1/00 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
28
Electrolytic cell components
30
Electrodes, e.g. test electrodes; Half-cells
327
Biochemical electrodes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
Applicants:
CALIFORNIA INSTITUTE OF TECHNOLOGY [US/US]; 1200 E California Blvd., M/C 6-32 Pasadena, California 91125, US
Inventors:
CHEN, Samson; US
SCHERER, Axel; US
JILANI, Muhammad Musab; US
MADERO, Xiomara L.; US
Agent:
STEINFL, Alessandro; US
BRUNO, Enrica; US
CASH, Brian J.; US
PEREZ, Ronald E,; US
DONG, Lun-Cong; US
XU, Jiancong; US
BRAMIAN, Tony; US
Priority Data:
62/564,92128.09.2017US
Title (EN) SWITCHABLE LOW VOLTAGE ELECTROCHEMICAL SENSING FOR INTERFERING SPECIES REJECTION
(FR) DÉTECTION ÉLECTROCHIMIQUE À BASSE TENSION COMMUTABLE POUR REJET D'ESPÈCES INTERFÉRENTES
Abstract:
(EN) A sensor implanted in tissues and including a sensing enzyme takes an electrical measurement and compares it to reference curves for the voltage current relationship. The sensor determines whether molecular compounds are present which interfere with the detection of the molecule of interest. If interfering species are found, the measurement voltage is set in a low range to reduce errors, while if the interfering species are not found, the measurement voltage is set in a high range to increase the detected signal.
(FR) Selon l'invention, un capteur implanté dans des tissus et comprenant une enzyme de détection prend une mesure électrique et la compare à des courbes de référence pour la relation courant-tension. Le capteur détermine si des composés moléculaires sont présents et qui interfèrent avec la détection de la molécule d'intérêt. Si des espèces interférentes sont trouvées, la tension de mesure est réglée dans une plage basse pour réduire les erreurs, tandis que si des espèces interférentes ne sont pas trouvées, la tension de mesure est réglée dans une plage haute pour augmenter le signal détecté.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)