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1. (WO2019067680) CROSSLINKING SUBMUCOSAL INJECTATE SYSTEM
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Pub. No.: WO/2019/067680 International Application No.: PCT/US2018/053060
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
A61L 31/04 (2006.01) ,A61L 31/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
04
Macromolecular materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
14
Materials characterised by their function or physical properties
Applicants:
COOK MEDICAL TECHNOLOGIES LLC [US/US]; 750 North Daniels Way Bloomington, IN 47404, US
Inventors:
SIGMON, John, C, Jr.; US
GITTARD, Shaun, D.; US
HARDY, Gregory, J.; US
CARRUTHERS, Christopher, A.; US
SCHAEFFER, Darin, G.; US
Agent:
DARE, Heidi, A.; US
Priority Data:
62/563,91227.09.2017US
Title (EN) CROSSLINKING SUBMUCOSAL INJECTATE SYSTEM
(FR) SYSTÈME D'INJECTION SOUS-MUQUEUSE À RÉTICULATION
Abstract:
(EN) A method of treating a lesion in a gastrointestinal tract and an injectate system are provided. The method includes injecting a crosslinkable gel into a first tissue layer, the crosslinkable gel increasing a volume of the first tissue layer. The method also includes providing a crosslinker and resecting a portion of a first tissue layer having the increased volume away from a second tissue layer creating an exposed region in a remaining portion of the first layer and leaving a portion of the gel covering at least a portion of the exposed region. The injectate system includes a crosslinkable gel and a crosslinker where the crosslinkable gel and the crosslinker form a crosslinked gel having a compressive modulus of about 10-500 kPa.
(FR) La présente invention concerne un procédé de traitement d'une lésion dans un tractus gastro-intestinal et un système d'injection. Le procédé comprend l'injection d'un gel réticulable dans une première couche de tissu, le gel réticulable augmentant un volume de la première couche de tissu. Le procédé comprend également la fourniture d'un agent de réticulation et la résection d'une partie d'une première couche de tissu ayant le volume accru à l'opposé d'une seconde couche de tissu créant une région exposée dans une partie restante de la première couche et laissant une partie du gel recouvrant au moins une partie de la région exposée. Le système d'injectat comprend un gel réticulable et un agent de réticulation, le gel réticulable et l'agent de réticulation formant un gel réticulé ayant un module de compression d'environ 10 à 500 kPa.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)