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1. (WO2019067677) METHODS OF MAKING BISPECIFIC ANTI-CD307E AND ANTI-BCMA CHIMERIC ANTIGEN RECEPTORS AND USES OF THE SAME
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Pub. No.: WO/2019/067677 International Application No.: PCT/US2018/053051
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
A61K 39/00 (2006.01) ,C07K 16/28 (2006.01) ,C07K 14/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Applicants:
CELL DESIGN LABS, INC. [US/US]; 5858 Horton St. Suite 240 Emeryville, CA 94608, US
Inventors:
EMTAGE, Peter; US
SANTORO, Stephen; US
SECREST, Stephanie; US
Agent:
DAMMANN, Yu-Ming; US
AMIRGHOLIZADEH, Tashica W.; US
BARRON, Briana R.; US
BOSS, Brandon; US
CHOI, Lydia B.; US
EDWARDS, Mary J.; US
GINAH, Francis O.; US
GRESSLER, Donna; US
HARTRUM, J. Elin; US
HUTCHISON, Andrea; US
MARQUART, Timothy A.; US
MORGAN, Lorie Ann; US
POLSTER, Philip B.; US
RICE, Katharine R.; US
SILVER, Joel; US
STUART, Tara C.; US
WAHLSTEN, Jennifer; US
YANG, Liuchun; US
Priority Data:
62/566,02529.09.2017US
Title (EN) METHODS OF MAKING BISPECIFIC ANTI-CD307E AND ANTI-BCMA CHIMERIC ANTIGEN RECEPTORS AND USES OF THE SAME
(FR) PROCÉDÉS DE FABRICATION DE RÉCEPTEURS D'ANTIGÈNES CHIMÉRIQUES ANTI-CD307E ET ANTI-BCMA BISPÉCIFIQUES ET LEURS UTILISATIONS
Abstract:
(EN) Provided herein are chimeric antigen receptors that binds specifically to B-cell maturation antigen (BCMA) and CD307e, nucleic acids that encode these chimeric antigen receptors, and methods of making and using these chimeric antigen receptors.
(FR) La présente invention concerne des récepteurs d'antigènes chimériques qui se lient spécifiquement à l'antigène de maturation des lymphocytes B (BCMA) et CD307e, des acides nucléiques qui codent ces récepteurs d'antigènes chimériques, et des procédés de fabrication et d'utilisation de ces récepteurs d'antigènes chimériques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)