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1. (WO2019067673) ERBB PEPTIDE PHARMACEUTICAL AND VACCINE COMPOSITIONS AND THERAPEUTICS USES THEREOF FOR CANCER
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Pub. No.: WO/2019/067673 International Application No.: PCT/US2018/053046
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
C07K 14/71 (2006.01) ,C07K 7/08 (2006.01) ,C07K 7/06 (2006.01) ,A61K 38/10 (2006.01) ,A61K 39/00 (2006.01) ,A61K 39/02 (2006.01) ,A61K 47/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
71
for growth factors; for growth regulators
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
08
having 12 to 20 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10
Peptides having 12 to 20 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
Applicants:
MAMULA, Mark [US/US]; US
KOSKI, Raymond, A. [US/US]; US
L2 DIAGNOSTICS, LLC [US/US]; 300 George Street, #309 New Haven, CT 06511-6662, US
Inventors:
MAMULA, Mark; US
KOSKI, Raymond, A.; US
Agent:
RUSSELL, Hathaway, P.; US
Priority Data:
62/563,85027.09.2017US
Title (EN) ERBB PEPTIDE PHARMACEUTICAL AND VACCINE COMPOSITIONS AND THERAPEUTICS USES THEREOF FOR CANCER
(FR) COMPOSITIONS PHARMACEUTIQUES ET VACCINALES À BASE D'UN PEPTIDE ERBB ET LEURS UTILISATIONS THÉRAPEUTIQUES POUR LE TRAITEMENT DU CANCER
Abstract:
(EN) Disclosed herein are peptide-adjuvant pharmaceutical compositions and vaccine compositions that trigger long lasting natural anti-tumor antibodies. Such compositions may be used alone, or in combination with anti-cancer agents, chemotherapeutic agents, anti-PD therapy, chemotherapy, radiation therapy, and surgery, in the prevention and treatment of cancer.
(FR) L'invention concerne des compositions pharmaceutiques et des compositions vaccinales à adjuvant peptidique qui déclenchent des anticorps anti-tumoraux naturels durables. Ces compositions peuvent être utilisées seules ou en association avec des agents anticancéreux, des agents chimiothérapeutiques, une thérapie anti-PD, une chimiothérapie, une radiothérapie et une chirurgie, pour prévenir ou guérir le cancer.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)