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1. (WO2019067656) POLYDOPAMINE-ENCAPSULATED NANODIAMONDS AND METHODS
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Pub. No.: WO/2019/067656 International Application No.: PCT/US2018/053010
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
A61K 31/704 (2006.01) ,A61K 47/02 (2006.01) ,A61K 47/48 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7028
Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034
attached to a carbocyclic compound, e.g. phloridzin
704
attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
02
Inorganic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
Applicants:
JUNG, Haksung [KR/US]; US (US)
NEUMAN, Keir Cajal [US/US]; US (US)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; National Institutes of Health Office of Technology Transfer 6011 Executive Boulevard Bethesda, Maryland 20892-7660, US
Inventors:
JUNG, Haksung; US
NEUMAN, Keir Cajal; US
Agent:
SHANER, Sandra, L.; US
Priority Data:
62/565,55229.09.2017US
Title (EN) POLYDOPAMINE-ENCAPSULATED NANODIAMONDS AND METHODS
(FR) NANODIAMANTS ENCAPSULÉS DANS UNE POLYDOPAMINE ET PROCÉDÉS ASSOCIÉS
Abstract:
(EN) A method of preparing a polydopamine-coated nanodiamond includes contacting a nanodiamond with dopamine in an alkaline aqueous solution under conditions effective to form a polydopamine-coated nanodiamond. A method of functionalizing a nanodiamond includes preparing a polydopamine-coated nanodiamond; and covalently coupling a compound comprising a functional group to the polydopamine of the polydopamine-coated nanodiamond. A nanodiamond prepared by the methods is also disclosed.
(FR) La présente invention concerne un procédé de préparation d'un nanodiamant revêtu d'une polydopamine qui consiste à mettre en contact un nanodiamant avec la dopamine dans une solution aqueuse alcaline dans des conditions efficaces pour former un nanodiamant revêtu d'une polydopamine. Un procédé de fonctionnalisation d'un nanodiamant consiste à préparer un nanodiamant revêtu d'une polydopamine ; et à coupler de manière covalente un composé comprenant un groupe fonctionnel avec la polydopamine du nanodiamant revêtu de polydopamine. L'invention concerne également un nanodiamant préparé par les procédés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)