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1. (WO2019067389) METHODS OF TREATING DEVELOPMENTAL DISORDERS AND/OR SEIZURE DISORDERS WITH ETIFOXINE
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Pub. No.: WO/2019/067389 International Application No.: PCT/US2018/052542
Publication Date: 04.04.2019 International Filing Date: 25.09.2018
IPC:
A61K 31/536 (2006.01) ,C07D 265/18 (2006.01) ,A61P 25/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
535
having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
536
ortho- or peri-condensed with carbocyclic ring systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
265
Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
04
1,3-Oxazines; Hydrogenated 1,3-oxazines
12
condensed with carbocyclic rings or ring systems
14
condensed with one six-membered ring
18
with hetero atoms directly attached in position 2
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
08
Antiepileptics; Anticonvulsants
Applicants:
OVID THERAPEUTICS INC. [US/US]; 1460 Broadway New York, New York 10036, US
Inventors:
DURING, Matthew; US
Agent:
STEEN, Jeffrey S.; US
CARTER, David M.; US
DELUCA, Peter; US
FARRELL, Raymond E.; US
BREW, Michael R.; US
Priority Data:
15/961,00224.04.2018US
62/563,15526.09.2017US
Title (EN) METHODS OF TREATING DEVELOPMENTAL DISORDERS AND/OR SEIZURE DISORDERS WITH ETIFOXINE
(FR) MÉTHODES DE TRAITEMENT DE TROUBLES DU DÉVELOPPEMENT ET/OU DE TROUBLES ÉPILEPTIQUES AVEC DE L'ÉTIFOXINE
Abstract:
(EN) Methods of treating developmental disorders and/or seizure disorders with etifoxine, a deuterated analog of etifoxine, or a pharmaceutically acceptable salt, solvate, or prodrug thereof are provided. The methods provide therapeutic compositions that may be used to improve one or more symptoms of the developmental disorder and/or seizure disorder.
(FR) L'invention concerne des méthodes de traitement de troubles du développement et/ou de troubles épileptiques avec de l'étifoxine, un analogue deutéré d'étifoxine, ou un sel, un solvate ou un promédicament pharmaceutiquement acceptable de celle-ci. Les méthodes fournissent des compositions thérapeutiques qui peuvent être utilisées pour améliorer un ou plusieurs symptômes des troubles du développement et/ou des troubles épileptiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)