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1. (WO2019067224) METHODS OF TREATING APOPTOSIS AND ALTERING PROGRAMMED CELL DEATH
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/067224 International Application No.: PCT/US2018/050856
Publication Date: 04.04.2019 International Filing Date: 13.09.2018
Chapter 2 Demand Filed: 13.05.2019
IPC:
A61K 31/44 (2006.01) ,A61P 7/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7
Drugs for disorders of the blood or the extracellular fluid
Applicants:
MYMD PHARMACEUTICALS, INC. [US/US]; 324 South Hyde Park Ave. Suite 350 Tampa, Florida 33606, US
Inventors:
WILLIAMS, Jonnie R.; US
Agent:
RIVARD, Paul; US
Priority Data:
62/565,24829.09.2017US
Title (EN) METHODS OF TREATING APOPTOSIS AND ALTERING PROGRAMMED CELL DEATH
(FR) PROCÉDÉS DE TRAITEMENT DE L'APOPTOSE ET DE MODIFICATION DE LA MORT CELLULAIRE PROGRAMMÉE
Abstract:
(EN) In one aspect, a method of altering programmed cell death includes administering to an individual in need thereof a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof. In other aspects, isomyosmine is administered to treat a wound, hemochromatosis, traumatic brain injury, or disorders associated with chronic oxidative stress. In other aspects, isomyosmine is administered to increase blood oxygen saturation levels.
(FR) Dans un aspect, un procédé de traitement d'un trouble associé à la mort cellulaire programmée inclut l’administration à un individu le nécessitant d’une quantité thérapeutiquement active d'isomyosmine ou de son sel pharmaceutiquement acceptable. Dans d'autres aspects, l'isomyosmine est administrée pour traiter une plaie, une hémochromatose, une lésion cérébrale traumatique ou des troubles associés à un stress oxydant chronique. Dans d'autres aspects, l'isomyosmine est administrée pour augmenter les taux de saturation en oxygène du sang.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)