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1. (WO2019067007) DIALYSATE FREE ARTIFICIAL KIDNEY DEVICE
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Pub. No.: WO/2019/067007 International Application No.: PCT/US2018/000004
Publication Date: 04.04.2019 International Filing Date: 26.01.2018
IPC:
B01D 61/24 (2006.01) ,B01D 61/28 (2006.01) ,B01D 61/32 (2006.01) ,B01D 61/44 (2006.01) ,B01D 61/48 (2006.01) ,B01D 61/50 (2006.01) ,B01D 61/54 (2006.01) ,B01D 61/02 (2006.01) ,B01D 61/12 (2006.01) ,B01D 61/14 (2006.01) ,B01D 61/58 (2006.01) ,C02F 1/469 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
24
Dialysis
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
24
Dialysis
28
Apparatus therefor
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
24
Dialysis
32
Controlling or regulating
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
42
Electrodialysis; Electro-osmosis
44
Ion-selective electrodialysis
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
42
Electrodialysis; Electro-osmosis
44
Ion-selective electrodialysis
46
Apparatus therefor
48
having one or more compartments filled with ion-exchange material
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
42
Electrodialysis; Electro-osmosis
44
Ion-selective electrodialysis
46
Apparatus therefor
50
Stacks of the plate-and-frame type
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
42
Electrodialysis; Electro-osmosis
44
Ion-selective electrodialysis
54
Controlling or regulating
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
02
Reverse osmosis; Hyperfiltration
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
02
Reverse osmosis; Hyperfiltration
12
Controlling or regulating
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
14
Ultrafiltration; Microfiltration
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
61
Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
58
Multistep processes
C CHEMISTRY; METALLURGY
02
TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
F
TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
1
Treatment of water, waste water, or sewage
46
by electrochemical methods
469
by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
Applicants:
CURION RESEARCH CORPORATION [US/US]; 2306 Thistle Down Drive Roseville, CA 95661, US
Inventors:
HESTEKIN, Jamie, Allen; US
HESTEKIN, Christa, Noel; US
MORRISON, Grace Ann, C.; US
PARACHA, Sadia, Ali; US
Agent:
BOCKMAN, Jonathan; US
Priority Data:
15/732,16927.09.2017US
Title (EN) DIALYSATE FREE ARTIFICIAL KIDNEY DEVICE
(FR) DISPOSITIF DE REIN ARTIFICIEL SANS DIALYSAT
Abstract:
(EN) A device and method are described for the treatment of blood, which device may be used in conjunction with or in place of a failed Kidney. The device includes an ultrafiltration unit to remove proteins, red and white blood cells and other high molecular weight components, a nanofiltration unit to remove glucose, at least one electrodeionization unit to transport ions from the blood stream, and a reverse osmosis unit to modulate the flow of water, to both the blood and urine streams. In one embodiment, a specialized electrodeionization unit is provided having multiple chambers defining multiple dilute fluid channels, each channel filled with an ion specific resin wafer, and electrodes at the extremity of the device and proximate each of the resin filled dilute channels. By selective application of voltages to these electrodes, the ion transport functionality of a given dilute channel can be turned on or off.
(FR) L'invention concerne un dispositif et un procédé pour le traitement du sang, lequel dispositif peut être utilisé conjointement avec rein défaillant ou à la place de celui-ci. Le dispositif comprend une unité d'ultrafiltration pour éliminer les protéines, les globules rouges et blancs et d'autres composants de poids moléculaire élevé, une unité de nanofiltration pour éliminer le glucose, au moins une unité d'électrodésionisation pour transporter des ions à partir du flux sanguin, et une unité d'osmose inverse pour moduler l'écoulement d'eau, vers les flux de sang et d'urine. Dans un mode de réalisation, une unité d'électrodésionisation spécialisée comprend de multiples chambres définissant de multiples canaux de fluide dilués, chaque canal étant rempli d'une tranche de résine spécifique aux ions, et des électrodes au niveau de l'extrémité du dispositif et à proximité de chacun des canaux dilués remplis de résine. Par application sélective de tensions à ces électrodes, la fonctionnalité de transport d'ions d'un canal dilué donné peut être activée ou désactivée.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)