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1. (WO2019066711) NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/066711 International Application No.: PCT/SE2018/050992
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
A61K 31/19 (2006.01) ,A61P 9/00 (2006.01) ,A61P 25/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants:
ELINDER, Fredrik [SE/SE]; SE
WU, Xiongyu; SE
OTTOSSON, Nina [SE/SE]; SE
KONRADSSON, Peter [SE/SE]; SE
SILVERÅ EJNEBY, Malin [SE/SE]; SE
Inventors:
ELINDER, Fredrik; SE
WU, Xiongyu; SE
OTTOSSON, Nina; SE
KONRADSSON, Peter; SE
SILVERÅ EJNEBY, Malin; SE
Agent:
BERGENSTRÅHLE & PARTNERS STOCKHOLM AB; P.O. Box 17704 118 93 Stockholm, SE
Priority Data:
1751207-029.09.2017SE
Title (EN) NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING
(FR) NOUVEAUX DÉRIVÉS DE DHAA AVEC ACCORD ÉLECTROSTATIQUE
Abstract:
(EN) Dehydroabietic acid derivatives according to Formula Ia or Formula Ib and all stereoisomers thereof, having a linker chain A of 1 to 10 atoms selected from carbon, nitrogen and oxygen to a group X capable of being negatively charged at a physiological pH and covalently attached to the linker chain A, selected from carboxyl, sulfate, sulfonate and phosphate groups. The Dehydroabietic acid derivatives are useful for therapeutic treatment of hyperexcitablity diseases
(FR) L'invention concerne des dérivés d'acide déhydroabiétique selon la Formule Ia ou la Formule Ib et tous les stéréoisomères de ceux-ci, ayant une chaîne de liaison A de 1 à 10 atomes choisis parmi le carbone, l'azote et l'oxygène à un groupe X pouvant être chargé négativement à un pH physiologique et fixé de manière covalente à la chaîne de liaison A, choisi parmi les groupes carboxyle, sulfate, sulfonate et phosphate. Les dérivés d'acide déhydroabiétique sont utiles pour le traitement thérapeutique de maladies d'hyperexcitabilité.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)