Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019066662) METHOD OF GENERATING HUMAN EPIDERMIS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/066662 International Application No.: PCT/NZ2018/050130
Publication Date: 04.04.2019 International Filing Date: 28.09.2018
IPC:
C12N 5/071 (2010.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
Applicants:
AUCKLAND UNISERVICES LIMITED [NZ/NZ]; Level 10, 49 Symonds Street Auckland, 1010, NZ
Inventors:
DUNBAR, Peter Roderick; NZ
FEISST, Vaughan John; NZ
Agent:
CATALYST INTELLECTUAL PROPERTY; Level 5, 45 Johnston Street Wellington, 6011, NZ
Priority Data:
1715928.630.09.2017GB
Title (EN) METHOD OF GENERATING HUMAN EPIDERMIS
(FR) PROCÉDÉ DE GÉNÉRATION D'ÉPIDERME HUMAIN
Abstract:
(EN) An in vitro method of generating a fully human epidermis (for example fully human full- thickness skin comprising a dermis and an epidermis] comprising a first step of culturing human keratinocytes and human fibroblast feeder cells in media comprising an effective amount of a ROCK inhibitor. Also provided is a skin product comprising a fully human epidermis produced using the disclosed method, including the use of the skin product for treatment.
(FR) L'invention concerne un procédé in vitro de génération d'un épiderme complètement humain (par exemple une peau complètement humaine de pleine épaisseur, comprenant un derme et un épiderme), comprenant une première étape de culture de kératinocytes humains et de cellules nourricières de fibroblastes humains dans des milieux comprenant une quantité efficace d'un inhibiteur ROCK. L'invention concerne également un produit de peau comprenant un épiderme complètement humain produit à l'aide du procédé selon l'invention, comprenant l'utilisation du produit de peau pour un traitement.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)