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1. (WO2019066649) METHOD FOR PREPARING MICRO-PARTICLES BY DOUBLE EMULSION TECHNIQUE
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Pub. No.: WO/2019/066649 International Application No.: PCT/NL2018/050636
Publication Date: 04.04.2019 International Filing Date: 26.09.2018
IPC:
A61K 9/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
Applicants:
NANOMI B.V. [NL/NL]; Zutphenstraat 51 7575 EJ Oldenzaal, NL
Inventors:
BLAZEJEWSKI, Emilie, Janine, Marie; NL
DUWEL, Robertus, Franciscus; NL
Agent:
JENSEN, C.M.; V.O. Carnegieplein 5 2517 KJ Den Haag, NL
Priority Data:
201963226.09.2017NL
Title (EN) METHOD FOR PREPARING MICRO-PARTICLES BY DOUBLE EMULSION TECHNIQUE
(FR) PROCÉDÉ DE PRÉPARATION DE MICROPARTICULES PAR UNE TECHNIQUE DE DOUBLE ÉMULSION
Abstract:
(EN) Methods for preparing micro-particles using a double emulsion technique combining a membrane and a micro-sieve are provided. Particularly the present invention relates to method for preparing micro-particles comprising: preparing a first phase comprising an active agent; preparing a second phase comprising a carrier and a solvent; passing the first phase and the second phase through a membrane to form a primary emulsion; passing the primary emulsion through a micro-sieve in a continuous phase to form a secondary emulsion; and removing the solvent to form the micro-particles.
(FR) L'invention concerne des procédés de préparation de microparticules à l'aide d'une technique de double émulsion combinant une membrane et un micro-tamis. En particulier, la présente invention concerne un procédé de préparation de microparticules comprenant : la préparation d'une première phase comprenant un agent actif; la préparation d'une seconde phase comprenant un support et un solvant; le passage de la première phase et de la seconde phase à travers une membrane pour former une émulsion primaire; le passage de l'émulsion primaire à travers un micro-tamis en phase continue pour former une émulsion secondaire; et l'élimination du solvant pour former les microparticules.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)