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1. (WO2019066632) NANOSTRUCTURE WHICH CAN PENETRATE DEEPLY INTO CANCER TISSUE
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Pub. No.: WO/2019/066632 International Application No.: PCT/KR2018/015536
Publication Date: 04.04.2019 International Filing Date: 07.12.2018
IPC:
A61K 9/51 (2006.01) ,A61K 47/26 (2006.01) ,A61K 31/704 (2006.01) ,A61K 45/06 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
51
Nanocapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7028
Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034
attached to a carbocyclic compound, e.g. phloridzin
704
attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
포항공과대학교 산학협력단 POSTECH ACADEMY-INDUSTRY FOUNDATION [KR/KR]; 경상북도 포항시 남구 청암로 77 77, Cheongam-ro, Nam-gu, Pohang-si, Gyeongsangbuk-do 37673, KR
Inventors:
김원종 KIM, Won Jong; KR
김진환 KIM, Jinhwan; KR
Agent:
특허법인 천지 CHEON JEE INTERNATIONAL PATENT & LAW FIRM; KR
Priority Data:
Title (EN) NANOSTRUCTURE WHICH CAN PENETRATE DEEPLY INTO CANCER TISSUE
(FR) NANOSTRUCTURE POUVANT PÉNÉTRER PROFONDÉMENT DANS UN TISSU CANCÉREUX
(KO) 암 조직 내 깊은 침투가 가능한 나노 구조체
Abstract:
(EN) The present invention relates to a nanostructure which can penetrate deeply into a cancer tissue and, more specifically, to a nanostructure which can selectively deliver a drug and nanoparticles to a cancer tissue by allowing the release of the drug and nanoparticles to be intelligently controlled according to the pH condition of the cancer tissue, and which also has a high nanoparticle and drug delivery efficiency by being capable of penetrating deeply into the cancer tissue.
(FR) La présente invention concerne une nanostructure qui peut pénétrer profondément dans un tissu cancéreux et, plus spécifiquement, une nanostructure qui peut administrer de manière sélective un médicament et des nanoparticules à un tissu cancéreux en permettant de réguler de manière intelligente la libération du médicament et des nanoparticules en fonction des conditions de pH du tissu cancéreux, et qui présente également une haute efficacité d'administration de nanoparticules et de médicament par sa capacité à pénétrer profondément dans le tissu cancéreux.
(KO) 본 발명은 암 조직 내 깊은 침투가 가능한 나노 구조체에 관한 것으로, 보다 상세하게는 암 조직의 pH 조건에 따라 나노입자 및 약물 방출을 지능적으로 제어가 가능함으로써, 선택적으로 암 조직에 나노입자 및 약물을 전달할 수 있고, 더불어 암 조직 내 깊은 침투가 가능함으로써 나노입자 및 약물 전달효율이 높은 나노구조체에 관한 것이다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)