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1. (WO2019066535) NOVEL RECOMBINANT PLASMA MEMBRANE-BASED VESICLE, FOR TREATING CANCER
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Pub. No.: WO/2019/066535 International Application No.: PCT/KR2018/011504
Publication Date: 04.04.2019 International Filing Date: 28.09.2018
IPC:
A61K 9/127 (2006.01) ,A61K 47/42 (2006.01) ,A61K 47/46 (2006.01) ,A61K 35/766 ,A61K 39/395 (2006.01) ,A61K 31/69 (2006.01) ,A61K 45/06 (2006.01) ,C07K 14/005 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
42
Proteins; Polypeptides; Degradation products thereof; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
46
Ingredients of undetermined constitution or reaction products thereof
[IPC code unknown for A61K 35/766]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
69
Boron compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
01
DNA viruses
03
Herpetoviridae, e.g. pseudorabies virus
05
Epstein-Barr virus
Applicants:
주식회사 탠덤 TANDEM CO., LTD. [KR/KR]; 서울시 강남구 강남대로 636, 3층 3rd Floor, 636, Gangnam-daero Gangnam-gu Seoul 06034, KR
Inventors:
김기범 KIM, Gi-Beom; KR
양유수 YANG, Yoo Soo; KR
김인산 KIM, In-San; KR
남기훈 NAM, Gihoon; KR
Agent:
한윤호 HAN, Yun Ho; KR
Priority Data:
10-2017-012620228.09.2017KR
Title (EN) NOVEL RECOMBINANT PLASMA MEMBRANE-BASED VESICLE, FOR TREATING CANCER
(FR) NOUVELLE VÉSICULE À BASE DE MEMBRANE PLASMIQUE RECOMBINANTE POUR LE TRAITEMENT DU CANCER
(KO) 암 치료용 신규 재조합 원형질막-기반 소포체
Abstract:
(EN) The present invention relates to a recombinant plasma membrane-based vesicle, and more specifically to a recombinant plasma membrane-based vesicle comprising a VSV-G mutated protein in which histidine, which is the 162nd amino acid in the membrane, has been replaced with arginine, and a pharmaceutical composition, for treating cancer, comprising the recombinant plasma membrane-based vesicle.
(FR) La présente invention concerne une vésicule à base de membrane plasmique recombinante, et plus spécifiquement, une vésicule à base de membrane plasmique recombinante comprenant une protéine mutée VSV-G dans laquelle l'histidine, qui est le 162ème acide aminé dans la membrane, a été remplacée par de l'arginine, ainsi qu'une composition pharmaceutique, pour le traitement du cancer, comprenant la vésicule à base de membrane plasmique recombinante.
(KO) 본 발명은 재조합 원형질막-기반 소포체에 관한 것으로서, 더 상세하게는 막에 162번째 아미노산인 히스티딘이 아르기닌으로 치환된 VSV-G 변이체 단백질을 포함하는 재조합 원형질막-기반 소포체 및 상기 재조합 원형질막-기반 소포체를 포함하는 암 치료용 약학적 조성물에 관한 것이다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)