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1. (WO2019066461) DETECTION OF TARGET NUCLEIC ACID SEQUENCES BY PTO CLEAVAGE AND EXTENSION-DEPENDENT EXTENSION ASSAY
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Pub. No.: WO/2019/066461 International Application No.: PCT/KR2018/011373
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
C12Q 1/6823 (2018.01) ,C12Q 1/6818 (2018.01) ,C12Q 1/6834 (2018.01) ,C12Q 1/6876 (2018.01)
[IPC code unknown for C12Q 1/6823][IPC code unknown for C12Q 1/6818][IPC code unknown for C12Q 1/6834][IPC code unknown for C12Q 1/6876]
Applicants:
SEEGENE, INC. [KR/KR]; 8FL., 9FL., 91, Ogeum-ro, Songpa-gu Seoul 05548, KR
Inventors:
LEE, Young Jo; KR
LEE, Han Bit; KR
KIM, Dae Young; KR
Agent:
YOON, Dae Woong; Suite 301, Chungdong Building 1922, Nambusunhwan-ro Gwanak-gu Seoul 08793, KR
Priority Data:
10-2017-012811029.09.2017KR
Title (EN) DETECTION OF TARGET NUCLEIC ACID SEQUENCES BY PTO CLEAVAGE AND EXTENSION-DEPENDENT EXTENSION ASSAY
(FR) DÉTECTION DE SÉQUENCES D'ACIDES NUCLÉIQUES CIBLES PAR ANALYSE PAR CLIVAGE ET EXTENSION DE PTO
Abstract:
(EN) The present invention relates to the detection of a target nucleic acid sequence by a PTOCE-E (PTO Cleavage and Extension-dependent Extension) assay. The PTOCE- E assay of the present invention can reduce the non-target signal and increase the target signal as compared with the conventional PTOCE and PCE-SH methods, thereby enabling more accurate detection of the target nucleic acid sequence.
(FR) La présente invention concerne la détection d'une séquence d'acide nucléique cible par analyse PTOCE-E (clivage et extension de PTO). L'analyse PTOCE-E de la présente invention peut réduire le signal non cible et augmenter le signal cible par comparaison avec les procédés PTOCE et PCE-SH traditionnels, permettant ainsi une détection plus précise de la séquence d'acide nucléique cible.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)