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1. (WO2019066434) COMPOSITION COMPRISING SAPOGENIN AND EXOSOME AS EFFECTIVE INGREDIENT
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Pub. No.: WO/2019/066434 International Application No.: PCT/KR2018/011316
Publication Date: 04.04.2019 International Filing Date: 21.09.2018
IPC:
A61K 8/63 (2006.01) ,A61K 8/14 (2006.01) ,A61K 31/58 (2006.01) ,A61K 31/585 (2006.01) ,A61K 9/127 (2006.01) ,A61Q 19/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
63
Steroids; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
02
characterised by special physical form
14
Liposomes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58
containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58
containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
585
containing lactone rings, e.g. oxandrolone, bufalin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
Applicants:
주식회사 엑소코바이오 EXOCOBIO INC. [KR/KR]; 서울시 금천구 가산디지털1로 19, 306호 Suite 306, 19, Gasan digital 1-ro Geumcheon-gu Seoul 08594, KR
Inventors:
이용원 YI, Yong Weon; KR
조병성 CHO, Byong Seung; KR
Agent:
이동기 LEE, Dong-Ki; KR
Priority Data:
10-2017-012846330.09.2017KR
10-2018-010987913.09.2018KR
Title (EN) COMPOSITION COMPRISING SAPOGENIN AND EXOSOME AS EFFECTIVE INGREDIENT
(FR) COMPOSITION COMPRENANT DE LA SAPOGÉNINE ET UN EXOSOME EN TANT QUE PRINCIPE ACTIF
(KO) 사포게닌과 엑소좀을 유효성분으로 포함하는 조성물
Abstract:
(EN) The present invention provides a composition comprising an exosome and sapogenin as an effective ingredient. A composition according to the present invention can promote preadipocyte proliferation, lipid accumulation in adipocytes, and/or adipocyte differentiation and reduce the cytotoxicity caused by a sapogenin ingredient. Therefore, the composition of the present invention can be conveniently applied to and used in an unsatisfactory body complex region in the sense of a small volume due to a lack of lipids, etc. and to a skin defective region due to insufficient lipids while reducing side effects on the human body or skin.
(FR) La présente invention concerne une composition comprenant un exosome et de la sapogénine au titre de principe actif. Une composition selon la présente invention peut favoriser la prolifération de pré-adipocytes, l'accumulation de lipides dans les adipocytes, et/ou la différenciation des adipocytes et réduire la cytotoxicité provoquée par un composant à base de sapogénine. Par conséquent, la composition de la présente invention peut être appliquée de manière pratique et être utilisée dans une région corporelle complexe non satisfaisante dans le sens d'un petit volume du fait d’un manque de lipides, etc. et une région défectueuse de la peau du fait d’une quantité insuffisante de lipides tout en réduisant les effets secondaires sur le corps humain ou la peau.
(KO) 본 발명은 엑소좀과 사포게닌을 유효성분으로 포함하는 조성물을 제공한다. 본 발명의 조성물은 지방전구세포 증식, 지방세포 내로의 지질 축적, 및/또는 지방세포로의 분화를 촉진하고 사포게닌 성분에 의한 세포독성을 감소킬 수 있다. 따라서 본 발명의 조성물은 신체나 피부에 대한 부작용을 줄이면서 지질부족 등으로 볼륨감이 작아 불만족스러운 신체 결함 부위나 지질부족에 기인한 피부 결함 부위에 간편하게 도포되어 사용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)