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1. WO2019066380 - COMPOSITION FOR PROMOTING ADIPOCYTE DIFFERENTIATION OR ADIPONECTIN, COMPRISING TRIMETHOXY PHENYL COMPOUND

Publication Number WO/2019/066380
Publication Date 04.04.2019
International Application No. PCT/KR2018/011124
International Filing Date 20.09.2018
IPC
A61K 8/49 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
A61K 8/67 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
67Vitamins
C07K 14/575 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
C12N 5/077 2010.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
077Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
A61Q 19/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
CPC
A23L 29/035
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
29Foods or foodstuffs containing additives
03Organic compounds
035containing oxygen as heteroatom
A23L 33/155
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
15Vitamins
155Vitamins A or D
A61K 31/351
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
351not condensed with another ring
A61K 47/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
A61K 8/4973
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
4973with oxygen as the only hetero atom
A61K 8/498
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
4973with oxygen as the only hetero atom
498having 6-membered rings or their condensed derivatives, e.g. coumarin
Applicants
  • (주)아모레퍼시픽 AMOREPACIFIC CORPORATION [KR]/[KR]
Inventors
  • 박필준 PARK, Pil Joon
  • 이태룡 LEE, Tae Ryong
  • 조은경 CHO, Eungyung
Agents
  • 김순영 KIM, Sun-young
Priority Data
10-2017-012740729.09.2017KR
Publication Language Korean (ko)
Filing Language Korean (KO)
Designated States
Title
(EN) COMPOSITION FOR PROMOTING ADIPOCYTE DIFFERENTIATION OR ADIPONECTIN, COMPRISING TRIMETHOXY PHENYL COMPOUND
(FR) COMPOSITION POUR FAVORISER LA DIFFÉRENCIATION ADIPOCYTAIRE OU LA PRODUCTION D'ADIPONECTINE, COMPRENANT UN COMPOSÉ DE TRIMÉTHOXY PHÉNYLE
(KO) 트리메톡시 페닐 화합물을 포함하는 지방세포 분화 또는 아디포넥틴 촉진용 조성물
Abstract
(EN) The present invention relates to a composition for promoting adipocyte differentiation or adiponectin production, comprising a trimethoxy phenyl compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof as an effective ingredient. A composition according to the present specification promotes adipocyte differentiation or adiponectin production, thereby exhibiting the effect of making the skin plump or increasing skin elasticity. Hence, the composition of the present specification can find various applications as a pharmaceutical composition or cosmetic composition in the field such as that concerning skin damage.
(FR) La présente invention concerne une composition comprenant un composé de triméthoxy phényle, un isomère de celui-ci, un sel pharmaceutiquement acceptable de celui-ci, un hydrate de celui-ci, ou un solvate de celui-ci en tant que principe actif pour favoriser la différenciation adipocytaire ou la production d'adiponectine. Une composition selon la présente invention favorise la différenciation adipocytaire ou la production d'adiponectine, ce qui a pour effet de repulper la peau ou d'augmenter l'élasticité de la peau. Par conséquent, la composition selon la présente invention peut trouver diverses applications en tant que composition pharmaceutique ou composition cosmétique dans le domaine tel que celui concernant les dommages cutanés.
(KO) 트리메톡시 페닐 화합물, 이의 이성질체, 이의 약학적으로 허용 가능한 염, 이의 수화물 또는 이의 용매화물을 유효 성분으로 포함하는 지방세포 분화 또는 아디포넥틴 생성 촉진용 조성물에 관한 것으로, 본 명세서에 따른 조성물은 지방세포 분화 또는 아디포넥틴 생성을 촉진시키고, 이러한 효과로 피부의 볼륨 또는 탄력을 증진시킬 수 있는 효과를 가진다. 따라서 본 명세서의 조성물은 피부 손상 같은 분야에서 약학 조성물 또는 화장료 조성물로서 다양하게 활용될 수 있다.
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