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1. (WO2019066380) COMPOSITION FOR PROMOTING ADIPOCYTE DIFFERENTIATION OR ADIPONECTIN, COMPRISING TRIMETHOXY PHENYL COMPOUND
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Pub. No.: WO/2019/066380 International Application No.: PCT/KR2018/011124
Publication Date: 04.04.2019 International Filing Date: 20.09.2018
IPC:
A61K 8/49 (2006.01) ,A61K 8/67 (2006.01) ,C07K 14/575 (2006.01) ,C12N 5/077 (2010.01) ,A61Q 19/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
49
containing heterocyclic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
67
Vitamins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
077
Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
Applicants:
(주)아모레퍼시픽 AMOREPACIFIC CORPORATION [KR/KR]; 서울시 용산구 한강대로 100 100, Hangang-daero, Yongsan-gu, Seoul 04386, KR
Inventors:
박필준 PARK, Pil Joon; KR
이태룡 LEE, Tae Ryong; KR
조은경 CHO, Eungyung; KR
Agent:
김순영 KIM, Sun-young; KR
Priority Data:
10-2017-012740729.09.2017KR
Title (EN) COMPOSITION FOR PROMOTING ADIPOCYTE DIFFERENTIATION OR ADIPONECTIN, COMPRISING TRIMETHOXY PHENYL COMPOUND
(FR) COMPOSITION POUR FAVORISER LA DIFFÉRENCIATION ADIPOCYTAIRE OU LA PRODUCTION D'ADIPONECTINE, COMPRENANT UN COMPOSÉ DE TRIMÉTHOXY PHÉNYLE
(KO) 트리메톡시 페닐 화합물을 포함하는 지방세포 분화 또는 아디포넥틴 촉진용 조성물
Abstract:
(EN) The present invention relates to a composition for promoting adipocyte differentiation or adiponectin production, comprising a trimethoxy phenyl compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof as an effective ingredient. A composition according to the present specification promotes adipocyte differentiation or adiponectin production, thereby exhibiting the effect of making the skin plump or increasing skin elasticity. Hence, the composition of the present specification can find various applications as a pharmaceutical composition or cosmetic composition in the field such as that concerning skin damage.
(FR) La présente invention concerne une composition comprenant un composé de triméthoxy phényle, un isomère de celui-ci, un sel pharmaceutiquement acceptable de celui-ci, un hydrate de celui-ci, ou un solvate de celui-ci en tant que principe actif pour favoriser la différenciation adipocytaire ou la production d'adiponectine. Une composition selon la présente invention favorise la différenciation adipocytaire ou la production d'adiponectine, ce qui a pour effet de repulper la peau ou d'augmenter l'élasticité de la peau. Par conséquent, la composition selon la présente invention peut trouver diverses applications en tant que composition pharmaceutique ou composition cosmétique dans le domaine tel que celui concernant les dommages cutanés.
(KO) 트리메톡시 페닐 화합물, 이의 이성질체, 이의 약학적으로 허용 가능한 염, 이의 수화물 또는 이의 용매화물을 유효 성분으로 포함하는 지방세포 분화 또는 아디포넥틴 생성 촉진용 조성물에 관한 것으로, 본 명세서에 따른 조성물은 지방세포 분화 또는 아디포넥틴 생성을 촉진시키고, 이러한 효과로 피부의 볼륨 또는 탄력을 증진시킬 수 있는 효과를 가진다. 따라서 본 명세서의 조성물은 피부 손상 같은 분야에서 약학 조성물 또는 화장료 조성물로서 다양하게 활용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)