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1. (WO2019066172) N-DEOXYRIBOSYL TRANSFERASE MUTANT AND NUCLEOSIDE PREPARING METHOD USING SAME
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Pub. No.: WO/2019/066172 International Application No.: PCT/KR2018/003473
Publication Date: 04.04.2019 International Filing Date: 23.03.2018
IPC:
C12N 9/10 (2006.01) ,C12N 15/70 (2006.01) ,C12P 19/18 (2006.01) ,C12P 19/38 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10
Transferases (2.)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
70
Vectors or expression systems specially adapted for E. coli
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
18
produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
26
Preparation of nitrogen-containing carbohydrates
28
N-glycosides
38
Nucleosides
Applicants:
에스티팜 주식회사 ST PHARM CO., LTD. [KR/KR]; 경기도 시흥시 협력로 231 231, Hyemnyeok-ro Siheung-si Gyeonggi-do 15086, KR
Inventors:
노갑수 NOH, Kap Soo; KR
김병균 KIM, Byung Kyun; KR
최강현 CHOI, Kang Hyun; KR
Agent:
안소영 AHN, So Young; KR
Priority Data:
10-2017-012744829.09.2017KR
Title (EN) N-DEOXYRIBOSYL TRANSFERASE MUTANT AND NUCLEOSIDE PREPARING METHOD USING SAME
(FR) MUTANT DE N-DÉSOXYRIBOSYLTRANSFÉRASE ET PROCÉDÉ DE PRODUCTION DE NUCLÉOSIDE À L'AIDE DE CELUI-CI
(KO) N-데옥시리보실 트랜스퍼라아제 변이체 및 이를 이용한 뉴클레오시드의 제조방법
Abstract:
(EN) The present invention relates to an N-deoxyribosyl transferase mutant, a polynucleotide coding for the mutant, a vector carrying the polynucleotide, a microorganism containing the polynucleotide, and a method for preparing a nucleoside, using the same vector and microorganism.
(FR) La présente invention concerne un mutant de N-désoxyribosyltransférase, un polynucléotide codant pour le mutant, un vecteur portant le polynucléotide, un micro-organisme contenant le polynucléotide, ainsi qu'un procédé de préparation d'un nucléoside, à l'aide de ces mêmes vecteur et micro-organisme.
(KO) 본 발명은 N-데옥시리보실 트랜스퍼라아제 변이체, 상기 변이체를 코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 벡터 및 미생물, 및 이를 이용한 뉴클레오시드의 제조방법에 관한 것이다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)