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1. (WO2019066010) PROPHYLACTIC OR THERAPEUTIC AGENT FOR NON-ALCOHOLIC STEATOHEPATITIS AND USE OF SAME
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Pub. No.: WO/2019/066010 International Application No.: PCT/JP2018/036389
Publication Date: 04.04.2019 International Filing Date: 28.09.2018
IPC:
A61K 31/352 (2006.01) ,A61P 1/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
16
for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Applicants:
国立研究開発法人産業技術総合研究所 NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY [JP/JP]; 東京都千代田区霞が関一丁目3番1号 3-1, Kasumigaseki 1-chome, Chiyoda-ku, Tokyo 1008921, JP
Inventors:
礒田 博子 ISODA Hiroko; JP
嶋本 康広 SHIMAMOTO Yasuhiro; JP
富永 健一 TOMINAGA Kenichi; JP
浅川 真澄 ASAKAWA Masumi; JP
佐藤 一彦 SATO Kazuhiko; JP
Agent:
西澤 和純 NISHIZAWA Kazuyoshi; JP
大槻 真紀子 OTSUKI Makiko; JP
大浪 一徳 ONAMI Kazunori; JP
Priority Data:
2017-18814428.09.2017JP
Title (EN) PROPHYLACTIC OR THERAPEUTIC AGENT FOR NON-ALCOHOLIC STEATOHEPATITIS AND USE OF SAME
(FR) AGENT PROPHYLACTIQUE OU THÉRAPEUTIQUE CONTRE LA STÉATOHÉPATITE NON ALCOOLIQUE ET SON UTILISATION
(JA) 非アルコール性脂肪性肝炎の予防又は治療剤及びその使用
Abstract:
(EN) A prophylactic or therapeutic agent for non-alcoholic steatohepatitis, which contains a compound represented by formula (1) as an active ingredient. (In formula (1), each of R1-R5 independently represents a hydrogen atom or a methyl group; and at least one of R1-R5 is a methyl group.)
(FR) L'invention concerne un agent prophylactique ou thérapeutique contre la stéatohépatite non alcoolique, qui contient un composé représenté par la formule (1) en tant que principe actif. (Dans la formule (1), chacun des R1 à R5 représente indépendamment un atome d'hydrogène ou un groupe méthyle ; et au moins l'un des R1 à R5 est un groupe méthyle.)
(JA) 下記式(1)(式(1)中、R~Rは、それぞれ独立に水素原子又はメチル基を表し、R~Rのうち少なくとも1つはメチル基である)で表される化合物を有効成分として含有する、非アルコール性脂肪性肝炎の予防又は治療剤。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)