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1. (WO2019065962) CASPASE 3 ACTIVITY INHIBITOR, APOPTOSIS INHIBITOR, INHIBITOR OF TOXICITY DUE TO SECONDARY BILE ACID, AND INTESTINAL TRACT DISORDER INHIBITOR
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Pub. No.: WO/2019/065962 International Application No.: PCT/JP2018/036247
Publication Date: 04.04.2019 International Filing Date: 28.09.2018
IPC:
A61K 36/31 (2006.01) ,A61P 1/00 (2006.01) ,A61P 1/04 (2006.01) ,A61P 1/16 (2006.01) ,A61P 3/06 (2006.01) ,A61P 35/00 (2006.01) ,A61P 43/00 (2006.01) ,C12N 9/99 (2006.01) ,A61K 127/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
31
Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
04
for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
16
for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
06
Antihyperlipidemics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
99
Enzyme inactivation by chemical treatment
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
127
Containing or obtained from leaves
Applicants:
株式会社アミノアップ化学 AMINO UP CHEMICAL CO., LTD. [JP/JP]; 北海道札幌市清田区真栄363番地32号 363-32, Shin-ei, Kiyota-ku, Sapporo-shi, Hokkaido 0040839, JP
Inventors:
▲高▼橋 のどか TAKAHASHI Nodoka; JP
平山 洋佑 HIRAYAMA Yosuke; JP
▲高▼野 翔 TAKANO Sho; JP
高橋 麻起子 TAKAHASHI Makiko; JP
後藤 一法 GOTO Kazunori; JP
Agent:
木村 満 KIMURA Mitsuru; JP
Priority Data:
2017-19124729.09.2017JP
Title (EN) CASPASE 3 ACTIVITY INHIBITOR, APOPTOSIS INHIBITOR, INHIBITOR OF TOXICITY DUE TO SECONDARY BILE ACID, AND INTESTINAL TRACT DISORDER INHIBITOR
(FR) INHIBITEUR DE L'ACTIVITÉ DE LA CASPASE 3, INHIBITEUR DE L'APOPTOSE, INHIBITEUR DE LA TOXICITÉ DUE À L'ACIDE BILIAIRE SECONDAIRE, ET INHIBITEUR DES TROUBLES DU TRACTUS INTESTINAL
(JA) カスパーゼ3活性抑制剤、アポトーシス抑制剤、二次胆汁酸による毒性抑制剤及び腸管障害抑制剤
Abstract:
(EN) This caspase 3 activity inhibitor uses horseradish leaf extract as an active ingredient, said extract being obtained by performing solvent extraction on horseradish leaves.
(FR) L'invention concerne un inhibiteur d'activité de la caspase 3 utilisant un extrait de feuille de raifort en tant que principe actif, ledit extrait étant obtenu par l'exécution d'une extraction par solvant sur les feuilles de raifort.
(JA) カスパーゼ3活性抑制剤は、ヤマワサビの葉を溶媒抽出することで得られたヤマワサビ葉抽出物を有効成分とする。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)