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1. (WO2019065838) DRUG CONTAINING PYRIDYLAMINOACETIC ACID COMPOUND
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Pub. No.: WO/2019/065838 International Application No.: PCT/JP2018/035931
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
A61K 31/444 (2006.01) ,A61K 9/08 (2006.01) ,A61P 27/02 (2006.01) ,A61P 43/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
444
containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27
Drugs for disorders of the senses
02
Ophthalmic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants:
参天製薬株式会社 SANTEN PHARMACEUTICAL CO., LTD. [JP/JP]; 大阪府大阪市東淀川区下新庄3丁目9番19号 9-19, Shimoshinjo 3-chome, Higashiyodogawa-ku, Osaka-shi, Osaka 5338651, JP
Inventors:
谷口 孝純 TANIGUCHI Takazumi; JP
赤石 貴浩 AKAISHI Takahiro; JP
中澤 仁志 NAKAZAWA Hitoshi; JP
Agent:
田中 伸一郎 TANAKA Shinichiro; JP
弟子丸 健 DESHIMARU Takeshi; JP
箱田 篤 HAKODA Atsushi; JP
浅井 賢治 ASAI Kenji; JP
山崎 一夫 YAMASAKI Kazuo; JP
市川 さつき ICHIKAWA Satsuki; JP
服部 博信 HATTORI Hironobu; JP
Priority Data:
2017-19075729.09.2017JP
Title (EN) DRUG CONTAINING PYRIDYLAMINOACETIC ACID COMPOUND
(FR) MÉDICAMENT CONTENANT UN COMPOSÉ D'ACIDE PYRIDYLAMINOACÉTIQUE
(JA) ピリジルアミノ酢酸化合物を含有する医薬
Abstract:
(EN) A novel medical use of omidenepag, an ester thereof, or salts of these has been discovered. As a result of thoroughgoing investigations to discover novel medical uses of omidenepag, an ester thereof, or salts of these, it was discovered that omidenepag, an ester thereof, or salts of these significantly dilate retinal blood vessels and significantly increase blood flow. Omidenepag, an ester thereof, or salts of these are therefore expected to protect retinal nerve cells and to be useful in the prevention and/or treatment of eye diseases that involve retinal nerve cell disorders.
(FR) L'invention concerne une nouvelle utilisation médicale d’omidenepag, d'un ester de celui-ci, ou de sels de ceux-ci. Grâce à des recherches approfondies pour découvrir de nouvelles utilisations médicales de l’omidenepag, d’un ester de celui-ci, ou de sels de ceux-ci, il a été découvert que l’omidenepag, un ester de celui-ci, ou des sels de ceux-ci dilatent significativement les vaisseaux sanguins rétiniens et augmentent significativement le débit sanguin. L’omidenepag, un ester de celui-ci, ou des sels de ceux-ci, sont donc censés protéger les cellules nerveuses rétiniennes et être utiles dans la prévention et/ou le traitement de maladies oculaires qui impliquent des troubles des cellules nerveuses rétiniennes.
(JA) オミデネパグ若しくはそのエステル又はそれらの塩の新たな医薬用途を見出すこと。オミデネパグ若しくはそのエステル又はそれらの塩の新たな医薬用途を見出すべく鋭意研究した結果、オミデネパグ若しくはそのエステル又はそれらの塩が、網膜血管を顕著に拡張させ、血流量を顕著に増加させることを見出した。従って、オミデネパグ若しくはそのエステル又はそれらの塩は、網膜神経細胞を保護し、網膜神経細胞障害が関与する眼疾患の予防及び/又は治療に有用であると期待される。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)