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1. (WO2019065674) OSTEOARTHRITIS IMPROVING AGENT
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Pub. No.: WO/2019/065674 International Application No.: PCT/JP2018/035563
Publication Date: 04.04.2019 International Filing Date: 26.09.2018
IPC:
A61K 31/221 (2006.01) ,A61P 19/02 (2006.01) ,A61P 29/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
221
with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
02
for joint disorders, e.g. arthritis, arthrosis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
Applicants:
アスタファーマシューティカルズ株式会社 ASTA PHARMACEUTICALS, CO., LTD. [JP/JP]; 富山県中新川郡上市町横法音寺55番地 55, Yokohoonji, Kamiichi-machi, Nakaniikawa-gun, Toyama 9300397, JP
Inventors:
横山 富久 YOKOYAMA, Tomihisa; JP
西田 康宏 NISHIDA, Yasuhiro; JP
Agent:
特許業務法人アルガ特許事務所 THE PATENT CORPORATE BODY ARUGA PATENT OFFICE; 東京都中央区日本橋人形町1丁目3番8号 沢の鶴人形町ビル Sawanotsuru Ningyocho Bldg., 1-3-8, Nihonbashi Ningyocho, Chuo-ku, Tokyo 1030013, JP
Priority Data:
2017-18587327.09.2017JP
Title (EN) OSTEOARTHRITIS IMPROVING AGENT
(FR) AGENT AMÉLIORANT L’ARTHROSE
(JA) 変形性関節症改善剤
Abstract:
(EN) To provide a novel osteoarthritis improving agent. An osteoarthritis improving agent which comprises a trans-astaxanthin derivative represented by formula (I), a geometric isomer thereof, a mixture of geometric isomers thereof, an optical isomer thereof or a salt thereof [in formula (I), m1, m2, n1 and n2 are the same or different and represent an integer of 1-6].
(FR) La présente invention concerne un nouvel agent améliorant l’arthrose. L’invention concerne un agent améliorant l’arthrose qui comprend un dérivé de trans-astaxanthine représenté par la formule (I), un isomère géométrique de celui-ci, un mélange d’isomères géométriques de celui-ci, un isomère optique de celui-ci ou un sel de celui-ci [dans la formule (I), m1, m2, n1 et n2 sont identiques ou différents et représentent un entier de 1 à 6].
(JA) 新たな変形性関節症改善剤の提供。 式(I)で示されるトランス-アスタキサンチン誘導体、その幾何異性体、それら幾何異性体の混合物、それらの光学異性体またはそれらの塩を含有する変形性関節症改善剤。 (式中、m1、m2、n1およびn2は、それぞれ同じまたは異なって1~6の整数を意味する。)
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)