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1. (WO2019064297) CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/064297 International Application No.: PCT/IL2018/051063
Publication Date: 04.04.2019 International Filing Date: 20.09.2018
IPC:
C07K 17/08 (2006.01) ,C07K 7/64 (2006.01) ,C07K 7/06 (2006.01) ,C12N 15/11 (2006.01) ,A61K 47/60 (2017.01) ,A61K 38/12 (2006.01) ,A61K 38/16 (2006.01) ,A61K 38/08 (2019.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
17
Carrier-bound or immobilised peptides; Preparation thereof
02
Peptides being immobilised on, or in, an organic carrier
08
the carrier being a synthetic polymer
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
64
Cyclic peptides containing only normal peptide links
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
[IPC code unknown for A61K 47/60]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12
Cyclic peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08
Peptides having 5 to 11 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
AEBI LTD. [IL/IL]; 13B Einstein Street, Weizmann Science Park P.O. Box 4010 70400 Ness Ziona, IL
Inventors:
MORAD, Ilan; IL
Agent:
WEBB, Cynthia; Webb & Co. P.O. Box 2189 7612101 Rehovot, IL
WEBB, Cynthia; IL
BARZAM, Maty; IL
BOGIN, Liora; IL
BURSTEIN, Tal; IL
FINAROV, Igal; IL
GANOR, Sharon; IL
HORNIK, Vered; IL
NOAH, Eran; IL
POTASH, Shay; IL
SCHICKLER, Hedva; IL
SCHVARTZ, Iris; IL
SILVERMAN, Eran; IL
TRAVITSKY, Nina; IL
WEBB, Yael; IL
ZIPOR, Gadi; IL
Priority Data:
62/563,66327.09.2017US
Title (EN) CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF
(FR) PEPTIDES CYTOTOXIQUES ET LEURS CONJUGUÉS
Abstract:
(EN) The present invention provides cytotoxic peptides, analogs thereof and fragments thereof, conjugates of said peptides, analogs or fragments as well as compositions comprising same. In addition, uses of these compounds and compositions in treating cancer are provided.
(FR) La présente invention concerne des peptides cytotoxiques, des analogues et des fragments de ceux-ci, des conjugués desdits peptides, analogues ou fragments, ainsi que des compositions les comprenant. L'invention concerne également des utilisations de ces composés et compositions dans le traitement du cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)